Results 251 to 260 of about 3,725,761 (393)

Repair replication in replicating and non-replicating DNA after irradiation with UV light [PDF]

, 1978
Hanoch Slor, James E. Cleaver
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Refined DNA repair manipulation enables a universal knock-in strategy in mouse embryos. [PDF]

Nat Commun
Chen H, Tan Q, Li L, Li L, Fu J, Zhu W, Li J, Wang Y, Li S, Li H, Sun Y, Sun Q, Lu Z, Liu Z.   +13 more
europepmc   +1 more source

DNA repair synthesis in human skin exposed to ultraviolet radiation used in PUVA (psoralen and UV-A) therapy for psoriasis [PDF]

, 1979
Simone C. Bishop
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Upregulation of POLE and proficient DNA repair are features of CIC::DUX4 sarcomas. [PDF]

NPJ Precis Oncol
Seligson ND, Paragji A, Shahalam F, Yilma B, Chen JL.   +4 more
europepmc   +1 more source

Levels of DNA polymerases α,β, and γ control and repair-deficient human diploid fibroblasts

, 1977
Vann P. Parker, Michael W. Lieberman
openalex   +2 more sources

Molecular mechanisms of DNA repair defects and heterogeneity in xeroderma pigmentosum [PDF]

, 1977
Hiraku Takebe
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Epigenetic Dysregulation in Cancer: Implications for Gene Expression and DNA Repair-Associated Pathways. [PDF]

Int J Mol Sci
Rembiałkowska N, Rekiel K, Urbanowicz P, Mamala M, Marczuk K, Wojtaszek M, Żywica M, Radzevičiūtė-Valčiukė E, Novickij V, Kulbacka J.   +9 more
europepmc   +1 more source