Results 251 to 260 of about 1,028,456 (338)

PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining at double-ended DSBs. [PDF]

Nucleic Acids Res
Ortega R, Taylor ER, Whitehead SM, Danhorn T, Bitler BG, Arnoult N.   +5 more
europepmc   +1 more source

Mutagenic DNA repair in enterobacteria

, 1991
Steven G. Sedgwick, C Ho, Roger Woodgate
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex. [PDF]

Nucleic Acids Res
Robu M, Shah RG, van den Heuvel D, Coulombe Y, Bazin M, van der Woude M, Kragten A, Lans H, Pascal JM, Masson JY, Luijsterburg MS, Shah GM.   +11 more
europepmc   +1 more source

Visualization of Repair of Double-Strand Breaks in the Bacteriophage T7 Genome without Normal DNA Replication

, 2000
Ying‐Ta Lai, Warren E. Masker
openalex   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Regulation of DNA repair gene expression by PRMT5. [PDF]

MicroPubl Biol
Bliss H, Bouley RA, Petreaca RC.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease

McHugh P, Roddan R, Schaich M, Nathan W, Kis I, Pierangelini A, Henderson L, Wee Rv, Martin L, El-Sagheer A, Kukura P, Brown T, O’Brien D, Newman J, iii DW, Schofield C, Houten B.   +16 more
europepmc   +1 more source

Pan-cancer profiling links C1orf50 to DNA repair and immune modulation in ovarian cancer. [PDF]

J Ovarian Res
Rogachevskaya A, Otani Y, Ohtsu A, Chin VD, Peña T, Arai S, Toyooka S, Fujimura A, Tanaka A.   +8 more
europepmc   +1 more source