Results 271 to 280 of about 3,725,761 (393)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Histone H1 deamidation facilitates chromatin relaxation for DNA repair. [PDF]

Nature
Tian Y, Feng T, Zhang J, Meng Q, Zhan W, Tang M, Liu C, Li M, Tao W, Shu Y, Zhang Y, Chen F, Takeda S, Zhu Q, Lu X, Zhu WG.   +15 more
europepmc   +1 more source

The sister chromatid exchange and the DNA repair replication in human chromosomes.

, 1978
Yukimasa Shiraishi
openalex   +2 more sources

The Linear Relationship between DNA Double-strand Breaks and Radiation Dose (30 MeV Electrons) is Converted into a Quadratic Function by Cellular Repair [PDF]

, 1980
M. Frankenberg-Schwager, D. Frankenberg, D. Blöcher, C. Adamczyk   +3 more
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition. [PDF]

Nat Commun
Mukherjee S, Garda C, Boffa L, Elia AR, Massara M, Balia MT, Brina D, Mosole S, Campagnari A, Cassanmagnago GA, Rinaldi A, Lazzaroni G, Jarrossay D, Morone D, Ceppi I, De Sillo R, Giacomini I, Craparotta I, Di Rito L, Barry S, Laczko E, Streb S, Meani F, Di Lascio S, Hynes N, Lugli E, Puccio S, Sammut SJ, Perriard U, Harder Y, Rossi L, Gasparri ML, Bolis M, Cejka P, Calcinotto A.   +34 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Different rate-limiting steps in excision repair of ultraviolet- and N-acetoxy-2-acetylaminofluorene-damaged DNA in normal human fibroblasts.

, 1977
Fahad Ahmed, R. B. Setlow
openalex   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Alterations of DNA Repair and Immune Infiltration in Radiation-Induced Intestinal Injury. [PDF]

Dose Response
Li J, Zhang H, Jia X, Guan J, Zong X, Li S, Lu X, He N, Song H, Ji K, Zhang M, Li J, Liu Q, Wang J, Xu C.   +14 more
europepmc   +1 more source