Results 291 to 300 of about 3,810,652 (392)

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Mutagenesis of the PALB2 WD40 domain identifies variants defective in interaction with BRCA2 and DNA repair. [PDF]

J Biol Chem
Gomes TT, Elias ABR, Huang H, Hu C, Nepomuceno TC, de Gregoriis G, Chrispim DS, Skaf LB, Szpunar FARL, Suarez-Kurtz G, Couch FJ, Monteiro ANA, Carvalho MA.   +12 more
europepmc   +1 more source

DNA Damage and Repair Biomarkers of Immunotherapy Response.

Cancer Discovery, 2017
K. Mouw, Michael S. Goldberg, P. Konstantinopoulos, A. D’Andrea   +3 more
semanticscholar   +1 more source

Faculty Opinions recommendation of The multiple antibiotic resistance operon of enteric bacteria controls DNA repair and outer membrane integrity.

, 2017
Michael G. Kurilla, Ann E. Eakin
openalex   +2 more sources

HAT1 functions as a lactyltransferase and mediates RPA1 lactylation to promote DNA repair and radioresistance in lung adenocarcinoma. [PDF]

Cell Death Dis
He J, Lai T, Zhao Y, Zhou Z, Zhou L, Tao D, Yang H, Li N, He Y, Yang S, Tang Z, Zeng S, Munai E, Liu Y, Tan Y, Zhou W, Wu Y.   +16 more
europepmc   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

KAT5-mediated acetylation of PC4 facilitates DNA repair by promoting chromatin reorganization. [PDF]

Nucleic Acids Res
Agrawal A, Sikder S, Singh S, Sharma RK, Pallaprolu N, Mitra K, Mondal S, Mukhopadhyay R, Sarkar J, Peraman R, Ravichandiran V, Kundu TK.   +11 more
europepmc   +1 more source

Role of Prednisone and 25(OH) Vitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We evaluated the role of 25‐hydroxy vitamin D, prednisone and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25‐hydroxy vitamin D [25(OH)D] levels and other potential risk factors with BMD measures (spine T‐scores) and osteoporosis ...
Nima Madanchi, Andrea Fava, Daniel W Goldman, Laurence S Magder, Michelle Petri   +4 more
wiley   +1 more source

RCC1 knockdown sensitizes drug-resistant colorectal cancer to 5-fluorouracil or doxorubicin by impairing DNA repair. [PDF]

Cancer Drug Resist
Li J, Meng Y, Ouyang X, Lin X, Wu Y, Kwok HF.   +5 more
europepmc   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

Advanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He, Yilong Wan, Yanbo Zhu, Bo Peng, Shengxiang Shao, Xinyi Zou, Zhenyu Han, Jiaxi Li, Sheng Ju, Xin Tong, Jun Zhao, Hansi Liang, Liuqing Zhang, Jiashi Xiong, Dong Jiang   +14 more
wiley   +1 more source