Results 351 to 360 of about 3,725,761 (393)

Interplay of replication timing, DNA repair, and translesion synthesis in UV mutagenesis in yeast. [PDF]

Nucleus
Sewell A, Wyrick JJ.
europepmc   +1 more source

Robust prediction of synthetic gRNA activity and cryptic DNA repair by disentangling cellular CRISPR cleavage outcomes. [PDF]

Nat Commun
Riesenberg S, Kanis P, Karlic R, Maricic T.   +3 more
europepmc   +1 more source

D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming. [PDF]

Nat Commun
Lang F, Kaur K, Fu H, Zaheer J, Ribeiro DL, Aladjem MI, Yang C.   +6 more
europepmc   +1 more source

Exercise serum promotes DNA damage repair and upregulates DNA repair genePNKPin colon cancer cells

Orange ST, Dodd E, Nath S, Bowden H, Jordan A, Smith H, Hedley A, Chukwuma I, Hickson I, Saha SS.   +9 more
europepmc   +1 more source

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DNA repair

Current Opinion in Cell Biology, 1993
Multiple DNA repair processes are required to maintain the integrity of the cellular genome. Recent advances, including elucidation of three-dimensional structures of DNA repair enzymes, and the cloning and characterization of DNA repair genes implicated in human inherited disease, have given new insights into the surprising complexity of cellular ...
D E, Barnes, T, Lindahl, B, Sedgwick
openaire   +2 more sources

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.

Annual Review of Biochemistry, 2004
DNA damage is a relatively common event in the life of a cell and may lead to mutation, cancer, and cellular or organismic death. Damage to DNA induces several cellular responses that enable the cell either to eliminate or cope with the damage or to ...
A. Sancar, L. Lindsey-Boltz, K. Unsal-Kaçmaz, S. Linn   +3 more
semanticscholar   +1 more source

DNA Repair and Mutagenesis

, 2006
DNA damage Mutations The reversal of base damage Base excision repair Nucleotide excision repair in prokaryotes Nucleotide excision repair in lower eukaryotes Nucleotide excision repair in mammalian cells: general considerations and chromatin dynamics ...
E. Friedberg, G. Walker, W. Siede
semanticscholar   +1 more source

DNA Repair

2016
Cellular chromosomal DNA is the principal target through which ionising radiation exerts it diverse biological effects. This chapter summarises the relevant DNA damage signalling and repair pathways used by normal and tumour cells in response to irradiation.
Kerstin, Borgmann, Sabrina, Köcher, Malte, Kriegs, Wael Yassin, Mansour, Ann Christin, Parplys, Thorsten, Rieckmann, Kai, Rothkamm   +6 more
openaire   +2 more sources

DNA topoisomerases and DNA repair

BioEssays, 1988
AbstractDNA topoisomerases are enzymes that can modify, and may regulate, the topological state of DNA through concerted breaking and rejoining of the DNA strands. They have been believed to be directly involved in DNA excision repair, and perhaps to be required for the control of repair as well. The vicissitudes of this hypothesis provide a noteworthy
Robert T. Johnson, C. S. Downes
openaire   +3 more sources