Results 351 to 360 of about 3,810,652 (392)

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay

Hough SH, Jhujh SS, Awwad SW, Lam S, Thomas JC, Lewis O, Mosler T, Bader AS, Bartik LE, McKee S, Amudhavalli SM, Colin E, Damseh N, Clement E, Cacheiro P, Majumdar A, Smedley D, Thiffault I, Vieira GZ, Belotserkovskaya R, Smerdon SJ, Beli P, Galanty Y, Carnie CJ, Stewart GS, Jackson SP.   +25 more
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Correction to 'Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair'. [PDF]

Nucleic Acids Res
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Moonlighting Role of Meiotic SYCP1 in Breast Cancer: A Chromatin-Bound Regulator of DNA Repair, Transcription, and Drug Resistance

Brennan L, Grinchuk O, Pachon M, Sou I, Fawcett C, Nogueira C, Guthrie M, Bates A, Hine M, Thomaz A, Hu Z, Fielding A, Davies O, Tee W, McClurg U.   +14 more
europepmc   +1 more source

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DNA repair

Current Opinion in Cell Biology, 1993
Multiple DNA repair processes are required to maintain the integrity of the cellular genome. Recent advances, including elucidation of three-dimensional structures of DNA repair enzymes, and the cloning and characterization of DNA repair genes implicated in human inherited disease, have given new insights into the surprising complexity of cellular ...
D E, Barnes, T, Lindahl, B, Sedgwick
openaire   +2 more sources

DNA Repair

2016
Cellular chromosomal DNA is the principal target through which ionising radiation exerts it diverse biological effects. This chapter summarises the relevant DNA damage signalling and repair pathways used by normal and tumour cells in response to irradiation.
Kerstin, Borgmann, Sabrina, Köcher, Malte, Kriegs, Wael Yassin, Mansour, Ann Christin, Parplys, Thorsten, Rieckmann, Kai, Rothkamm   +6 more
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DNA topoisomerases and DNA repair

BioEssays, 1988
AbstractDNA topoisomerases are enzymes that can modify, and may regulate, the topological state of DNA through concerted breaking and rejoining of the DNA strands. They have been believed to be directly involved in DNA excision repair, and perhaps to be required for the control of repair as well. The vicissitudes of this hypothesis provide a noteworthy
C S, Downes, R T, Johnson
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DNA Repair in Plants

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Seisuke, Kimura, Kengo, Sakaguchi
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DNA Repair

Angewandte Chemie International Edition, 2015
DNA is constantly damaged by various endogenous and exogenous events. Repair systems constantly scan the genome for DNA lesions and replace damaged and mismatched bases, which finally enables the complex DNA double strand to store genetic information. This year's Nobel Prize in Chemistry was awarded to pioneers in this field, T. Lindahl, P.
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DNA-repair enzymes

Current Opinion in Structural Biology, 1997
Recent crystallographic studies of DNA-repair enzymes have provided the structural basis for the recognition of damaged DNA. The results imply that flipping out of the base is a common and crucial event in DNA repair. Two classes of repair enzymes that recognize distinct types of damage may exist.
D G, Vassylyev, K, Morikawa
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Photoaging and DNA repair

Journal of Dermatological Science, 2008
The incidence of sunlight-induced skin changes (photoaged skin, skin carcinogenesis) increases with increasing age and it is thought to be associated with an accumulation of mutations in skin cells. These mutations are mainly caused by UV exposure. The reactive oxygen species produced in UV-exposed skin can cause various kinds of DNA damages e.g., 8 ...
Shinichi, Moriwaki, Yoshito, Takahashi
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