Results 151 to 160 of about 1,049,873 (288)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase. [PDF]

Nat Commun
Harman A, Kartawinata M, Maroun NM, Nguyen DR, Rahman S, Hughes WE, Winardi K, Cohen SB, Cesare AJ, Lamm N, Bryan TM.   +10 more
europepmc   +1 more source

Papillomavirus DNA Replication

Intervirology, 1994
L T, Chow, T R, Broker
openaire   +2 more sources

Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis

, 2005
Ganna Bilousova, Andriy Marusyk, Christopher C. Porter, Robert D. Cardiff, James DeGregori   +4 more
openalex   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Structural basis for DNA replication by the African swine fever virus polymerase. [PDF]

iScience
Hu Z, SunKang Y, Liu Z, Huang L, Qi W, Yan R.   +5 more
europepmc   +1 more source

A Link among DNA Replication, Recombination, and Gene Expression Revealed by Genetic and Genomic Analysis of TEBICHI Gene of Arabidopsis thaliana

, 2009
Soichi Inagaki, Kenzo Nakamura, Atsushi Morikami   +2 more
openalex   +2 more sources

The Phosphorylation Network for Efficient Activation of the DNA Replication Checkpoint in Fission Yeast [PDF]

, 2011
Ming Yue, Amanpreet Singh, Zhuo Wang, Yong-jie Xu   +3 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions. [PDF]

Nat Commun
Tomkins J, Edwardes LV, Faull SV, Peach M, Gillespie PJ, Leber V, Schmidt A, Bounoua H, Sim N, Camarillo R, Blow JJ, Barr AR, Barnard A, Speck C.   +13 more
europepmc   +1 more source