Results 231 to 240 of about 1,048,189 (263)

DNA replication in primary hepatocytes without the six-subunit ORC. [PDF]

open access: yesElife
Przanowska RK   +11 more
europepmc   +1 more source
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Fidelity of mammalian DNA replication and replicative DNA polymerases

Biochemistry, 1991
Current models suggest that two or more DNA polymerases may be required for high-fidelity semiconservative DNA replication in eukaryotic cells. In the present study, we directly compare the fidelity of SV40 origin-dependent DNA replication in human cell extracts to the fidelity of mammalian DNA polymerases alpha, delta, and epsilon using lacZ alpha of ...
D C, Thomas   +8 more
openaire   +2 more sources

DNA replication licensing

Frontiers in Bioscience, 2004
The DNA replication licensing system ensures that chromosomal DNA is replicated precisely once before cell division occurs. A DNA helicase must be loaded on origin DNA for replication to initiate. Considerable evidence suggests that the MCM complex acts as a replicative helicase in eukaryotes.
H, Nishitani, Z, Lygerou
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The coupling of epigenome replication with DNA replication

Current Opinion in Plant Biology, 2011
In multicellular organisms, each cell contains the same DNA sequence, but with different epigenetic information that determines the cell specificity. Semi-conservative DNA replication faithfully copies the parental nucleotide sequence into two DNA daughter strands during each cell cycle.
Qian, Liu, Zhizhong, Gong
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Eukaryotic DNA Replication

Annual Review of Biochemistry, 1986
ADENOVIRUS 736 Genome Structure and Replication Mode 736 In Vitro Replication 736 SV40 DNA REPLICATION 739 The Role ofT Antigen in Initiation . 740 DNA Sequences Required for Replication 742 In Vitro Replication Systems 744 Proteins Required/or SV40 DNA Replication In Vitro 745 DNA Sequences Required 746 Minimal Origins Used In Vitro
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Defects and DNA Replication

Physical Review Letters, 2010
We introduce a rate-equation formalism to study DNA replication kinetics in the presence of defects resulting from DNA damage and find a crossover between two regimes: a normal regime, where the influence of defects is local, and an initiation-limited regime.
Michel G, Gauthier   +2 more
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PROKARYOTIC DNA REPLICATION

Annual Review of Biochemistry, 1992
PERSPECTIVES AND SUMMARY ..... 673 INTRODUCTION TO REPLICATION OPERATIONS 674 ELONGATION..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 677 The DNA Polymerase Complexes 677 Primosomes .. . .... . ... .. . ..... . ...... . . ...... ... . . . ....... ... . .....
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