Results 241 to 250 of about 1,048,189 (263)
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DNA replication in thermophiles
Biochemical Society Transactions, 2004DNA replication enzymes in the thermophilic Archaea have previously attracted attention due to their obvious use in methods such as PCR. The proofreading ability of the Pyrococcus furiosus DNA polymerase has resulted in a commercially successful product (Pfu polymerase).
A I, Majerník +2 more
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On the mechanism of DNA replication
Journal of Theoretical Biology, 1965Abstract A mechanism of DNA replication is proposed which involves a bifunctional replicase enzyme. Evidence is cited indicating that the major groove of the DNA helix represents the site of its replication. Base pairing and synthesis of single strands is pictured as occurring simultaneously on opposing sides of the groove, thus involving bases which
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1986
We have explored various strategies for exploiting the yeast genetic and biochemical system for understanding DNA replication. Because of the long time that has intervened between the isolation of random replication mutants of yeast and the identification of the gene products affected, an alternative approach to elucidating the molecular basis of ...
J L, Campbell +6 more
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We have explored various strategies for exploiting the yeast genetic and biochemical system for understanding DNA replication. Because of the long time that has intervened between the isolation of random replication mutants of yeast and the identification of the gene products affected, an alternative approach to elucidating the molecular basis of ...
J L, Campbell +6 more
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Papillomavirus DNA Replication
2003Papillomavirus genomes replicate and are maintained as stable extrachromosomal plasmid DNA (episomes) in many cell lines (reviewed in ref. 1). This process requires the viral E1 and E2 proteins and the origin of replication (2,3). The minimal origin of replication consists of an E1 binding site, an E2 binding site, and an AT rich region that probably ...
M C, Ferran, A A, McBride
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Journal of Theoretical Biology, 1972
Abstract The single postulate that proteins called π exist which recognize specific sequences (π sequences) in DNA and there cause the appropriate DNA polymerase to initiate synthesis of a polydeoxynucleotide chain provides an explanation of all the experimental observations relevant to DNA replication.
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Abstract The single postulate that proteins called π exist which recognize specific sequences (π sequences) in DNA and there cause the appropriate DNA polymerase to initiate synthesis of a polydeoxynucleotide chain provides an explanation of all the experimental observations relevant to DNA replication.
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Annual Review of Genetics, 2014
DNA replication is essential for all life forms. Although the process is fundamentally conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic studies have demonstrated that the process and the proteins involved in archaeal DNA replication are more similar to those in eukaryal DNA replication than in bacterial DNA ...
Lori M, Kelman, Zvi, Kelman
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DNA replication is essential for all life forms. Although the process is fundamentally conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic studies have demonstrated that the process and the proteins involved in archaeal DNA replication are more similar to those in eukaryal DNA replication than in bacterial DNA ...
Lori M, Kelman, Zvi, Kelman
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Microtubules and DNA Replication
1987Publisher Summary This chapter discusses the microtubules and DNA replication. The investigations of the role of microtubules in regulating DNA replication reflect two different schools of thought: one studied lymphocytes with the working hypothesis that cell surface-associated microtubules were required for the transmission of the mitogenic signal ...
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Current Opinion in Cell Biology, 1994
The past year has seen the genetic characterization of a human replication origin as well as the identification and characterization of some key components of replication initiation complexes in budding yeast. These results should provide important information for determining how the initial events in DNA replication are regulated during the eukaryotic
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The past year has seen the genetic characterization of a human replication origin as well as the identification and characterization of some key components of replication initiation complexes in budding yeast. These results should provide important information for determining how the initial events in DNA replication are regulated during the eukaryotic
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Nature, 1971
Bacterial cells seem to differentiate between thymine and thymidine, using them separately for replication and repair synthesis respectively. These two processes thus seem to draw their precursors from separate pools.
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Bacterial cells seem to differentiate between thymine and thymidine, using them separately for replication and repair synthesis respectively. These two processes thus seem to draw their precursors from separate pools.
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