Results 241 to 250 of about 3,738,521 (387)
Polyoma DNA synthesis in isolated nuclei: evidence for defective replication forks [PDF]
Gunnar Bjursell+2 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Multigenerational cell tracking of DNA replication and heritable DNA damage. [PDF]
Panagopoulos A+12 more
europepmc +1 more source
An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication [PDF]
James J. Champoux, Renato Dulbecco
openalex +1 more source
Processing ribonucleotides incorporated during eukaryotic DNA replication
Jessica S. Williams, S. Lujan, T. Kunkel
semanticscholar +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Editorial: DNA replication barriers and the origins of cancer. [PDF]
Fragkos M.
europepmc +1 more source
Autorepressor Model for Control of DNA Replication [PDF]
Lauren Sompayrac, O. Maaløe
openalex +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source