Results 241 to 250 of about 3,431,424 (346)

The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication. [PDF]

Nat Commun
Matsuhashi K, Ito KK, Nagai K, Sanada A, Watanabe K, Takumi K, Toyoda A, Fukuyama M, Yamamoto S, Chinen T, Stewart GS, Hata S, Kitagawa D.   +12 more
europepmc   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication. [PDF]

Nat Commun
Li D, Zhang ZM, Mei L, Yu Y, Guo Y, Mackintosh SG, Chen J, Allison DF, Kim A, Storey AJ, Edmondson RD, Byrum SD, Tackett AJ, Cai L, Cook JG, Song J, Wang GG.   +16 more
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Author Correction: Structures of the human leading strand Polε–PCNA holoenzyme

Nature Communications
Qing He, Feng Wang, Nina Y. Yao, Michael E. O’Donnell, Huilin Li   +4 more
doaj   +1 more source

Editorial: DNA replication barriers and the origins of cancer. [PDF]

Front Cell Dev Biol
Fragkos M.
europepmc   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Host Cell Protein MCM7 Interacts with NP1 of Minute Virus of Canines and Facilitates Viral DNA Replication. [PDF]

Microorganisms
Hei Z, Ren X, Ji K, Zhang Z, Chen B, Sun Y.   +5 more
europepmc   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

Multigenerational cell tracking of DNA replication and heritable DNA damage. [PDF]

Nature
Panagopoulos A, Stout M, Kilic S, Leary P, Vornberger J, Pasti V, Galarreta A, Lezaja A, Kirschenbühler K, Imhof R, Rehrauer H, Ziegler U, Altmeyer M.   +12 more
europepmc   +1 more source