Results 261 to 270 of about 1,032,448 (308)
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The coupling of epigenome replication with DNA replication
Current Opinion in Plant Biology, 2011In multicellular organisms, each cell contains the same DNA sequence, but with different epigenetic information that determines the cell specificity. Semi-conservative DNA replication faithfully copies the parental nucleotide sequence into two DNA daughter strands during each cell cycle.
Qian, Liu, Zhizhong, Gong
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Frontiers in Bioscience, 2004
The DNA replication licensing system ensures that chromosomal DNA is replicated precisely once before cell division occurs. A DNA helicase must be loaded on origin DNA for replication to initiate. Considerable evidence suggests that the MCM complex acts as a replicative helicase in eukaryotes.
H, Nishitani, Z, Lygerou
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The DNA replication licensing system ensures that chromosomal DNA is replicated precisely once before cell division occurs. A DNA helicase must be loaded on origin DNA for replication to initiate. Considerable evidence suggests that the MCM complex acts as a replicative helicase in eukaryotes.
H, Nishitani, Z, Lygerou
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Annual Review of Biochemistry, 1992
PERSPECTIVES AND SUMMARY ..... 673 INTRODUCTION TO REPLICATION OPERATIONS 674 ELONGATION..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 677 The DNA Polymerase Complexes 677 Primosomes .. . .... . ... .. . ..... . ...... . . ...... ... . . . ....... ... . .....
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PERSPECTIVES AND SUMMARY ..... 673 INTRODUCTION TO REPLICATION OPERATIONS 674 ELONGATION..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 677 The DNA Polymerase Complexes 677 Primosomes .. . .... . ... .. . ..... . ...... . . ...... ... . . . ....... ... . .....
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Nature Cell Biology, 2016
The function and regulation of repetitive DNA, the 'dark matter' of the genome, is still only rudimentarily understood. Now a study investigating DNA replication of repetitive centromeric chromosome segments has started to expose a fascinating replication program that involves suppression of ATR signalling, in particular during replication stress.
Tognetti, S, Speck, C
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The function and regulation of repetitive DNA, the 'dark matter' of the genome, is still only rudimentarily understood. Now a study investigating DNA replication of repetitive centromeric chromosome segments has started to expose a fascinating replication program that involves suppression of ATR signalling, in particular during replication stress.
Tognetti, S, Speck, C
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Annual Review of Biochemistry, 1986
ADENOVIRUS 736 Genome Structure and Replication Mode 736 In Vitro Replication 736 SV40 DNA REPLICATION 739 The Role ofT Antigen in Initiation . 740 DNA Sequences Required for Replication 742 In Vitro Replication Systems 744 Proteins Required/or SV40 DNA Replication In Vitro 745 DNA Sequences Required 746 Minimal Origins Used In Vitro
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ADENOVIRUS 736 Genome Structure and Replication Mode 736 In Vitro Replication 736 SV40 DNA REPLICATION 739 The Role ofT Antigen in Initiation . 740 DNA Sequences Required for Replication 742 In Vitro Replication Systems 744 Proteins Required/or SV40 DNA Replication In Vitro 745 DNA Sequences Required 746 Minimal Origins Used In Vitro
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Current Opinion in Genetics & Development, 2002
The study of DNA replication in eukaryotic chromosomes has revealed a multitude of different regulatory levels. Nuclear and chromosomal location as well as chromatin structure may affect the activity of replication origins and their modulation during development.
Susan A, Gerbi, Anja Katrin, Bielinsky
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The study of DNA replication in eukaryotic chromosomes has revealed a multitude of different regulatory levels. Nuclear and chromosomal location as well as chromatin structure may affect the activity of replication origins and their modulation during development.
Susan A, Gerbi, Anja Katrin, Bielinsky
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Annual Review of Genetics, 2014
DNA replication is essential for all life forms. Although the process is fundamentally conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic studies have demonstrated that the process and the proteins involved in archaeal DNA replication are more similar to those in eukaryal DNA replication than in bacterial DNA ...
Lori M, Kelman, Zvi, Kelman
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DNA replication is essential for all life forms. Although the process is fundamentally conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic studies have demonstrated that the process and the proteins involved in archaeal DNA replication are more similar to those in eukaryal DNA replication than in bacterial DNA ...
Lori M, Kelman, Zvi, Kelman
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On the mechanism of DNA replication
Journal of Theoretical Biology, 1965Abstract A mechanism of DNA replication is proposed which involves a bifunctional replicase enzyme. Evidence is cited indicating that the major groove of the DNA helix represents the site of its replication. Base pairing and synthesis of single strands is pictured as occurring simultaneously on opposing sides of the groove, thus involving bases which
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On the Processivity of DNA Replication
Journal of Biomolecular Structure and Dynamics, 1983In this paper we describe the nature and importance of processive enzymatic reactions in biological processes. A model is set up to describe the processive synthetic process in DNA replication, and experiments are presented to define and test the model, using the components of the T4 phage-coded five-protein (in vitro) DNA replication system of Alberts.
F R, Fairfield +3 more
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Journal of Cellular Biochemistry, 1999
One of the fundamental characteristics of life is the ability of an entity to reproduce itself, which stems from the ability of the DNA molecule to replicate itself. The initiation step of DNA replication, where control over the timing and frequency of replication is exerted, is poorly understood in eukaryotes in general, and in mammalian cells in ...
M, Zannis-Hadjopoulos, G B, Price
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One of the fundamental characteristics of life is the ability of an entity to reproduce itself, which stems from the ability of the DNA molecule to replicate itself. The initiation step of DNA replication, where control over the timing and frequency of replication is exerted, is poorly understood in eukaryotes in general, and in mammalian cells in ...
M, Zannis-Hadjopoulos, G B, Price
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