Results 271 to 280 of about 3,431,424 (346)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. [PDF]

Nucleic Acids Res
Krishnan SS, Shen Y, O'Hagan TB, Matthews LA, Weerasinghe NW, Ghirlando R, Thibodeaux CJ, Guarné A.   +7 more
europepmc   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

Advanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong, Hyuna Kwak, Woojin Jeong, Hongwoo Lee, Su‐Ji Jeon, Hyo‐Jun Lee, Pil Joon Seo, Seon‐Yeong Kwak   +7 more
wiley   +1 more source

Computational prediction of diagnostic biomarker candidates and prognostic gene signature from DNA replication-related genes in breast cancer. [PDF]

Discov Oncol
Sucularli C.
europepmc   +1 more source

Studies on the Temperature-dependent DNA Replication of the Herpesvirus of the Turkey in Chicken Embryo Fibroblasts

, 1979
Christine Kaschka‐Dierich, R. Thomssen
openalex   +1 more source

Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers

Advanced Functional Materials, EarlyView.
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto, Noelia Ruiz‐González, Valerio Di Carlo, Daniel Sánchez‐deAlcázar, Florencia Lezcano, Anna Pushkareva Fazullina, Samuel Sánchez   +6 more
wiley   +1 more source

Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells. [PDF]

J Biol Chem
Hassan O, Pizzagalli M, Leary OP, Zepecki JP, Corseri A, Wu LJ, Sasipalli S, Lee D, Hayward L, Tran L, Fajardo E, Fiser A, Karambizi D, Tapinos N.   +13 more
europepmc   +1 more source

Repair Replication: a Density-gradient Analysis of DNA from Cells Infected with Mengovirus or Newcastle Disease Virus

, 1972
Roger Hand, Igor Tamm
openalex   +1 more source

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

Advanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra, Liwen Zhang, Tianqi Guo, Sašo Ivanovski, Ruirui Qiao, Karan Gulati   +5 more
wiley   +1 more source