Results 121 to 130 of about 2,453,331 (300)
Cytosine-to-Uracil Deamination by SssI DNA Methyltransferase [PDF]
, 2013 The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation.
Stier, Ildikó +5 more
core +2 more sources
Restriction enzymes used in this study.
, 2021 The names and recognition sequences (restriction sites) of the restriction enzymes that were used to produce experimental dually labeled DNA barcodes. Note that the complement recognition sequences of each listed recognition sequences is a palindromic ...
Fredrik Westerlund (1285863) +4 more
core +1 more source
Isolasi karakterisasi dan uji ekspresi gen ALP1 SI Escherichia coli DH5a
Journal of Biological Researches, 1999 Amylase gene (ALP1) insertion in YCp 50 cloning vector was detected by Direct Screening PCR. Result of Direct Screening PCR showed one transformants which assumed have amylase gene insert.
Ni Nyoman Tri Puspaningsih +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
On the DNA cleavage mechanism of Type I restriction enzymes [PDF]
, 2017 Although the DNA cleavage mechanism of Type I restriction-modification enzymes has been extensively studied, the mode of cleavage remains elusive. In this work, DNA ends produced by EcoKI, EcoAI and EcoR124I, members of the Type IA, IB and IC families ...
Jindrova, Eva +4 more
core
PCR-RFLP diagnostic method for identifying Globodera species in Slovenia [PDF]
, 2011 Species identification within the genus Globodera is based on the morphological and morphometrical characters of the cysts and second stage juveniles, and these are included in the majority of identification keys.
ŠIRCA, Sasa; Agricultural Institute of Slovenia +3 more
core +1 more source
Journal of New Results in Science, 2015 In addition to traditional methods, investigation of rDNA gene regions with molecular techniques is widely used to identify insect taxa. In this study, the usability of the primers (TrITS2, 28S-D2) belonging to second expansion segment (D2) of the 28S ...
Ilyas Can, Yasar Gulmez
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The impact of the C-terminal domain on the interaction of human DNA topoisomerase II α and β with DNA [PDF]
, 2011 <b>Background</b> Type II DNA topoisomerases are essential, ubiquitous enzymes that act to relieve topological problems arising in DNA from normal cellular activity.
Caroline A. Austin +7 more
core +2 more sources