Results 281 to 290 of about 465,116 (357)

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes.

Gene, 1980
W. Loenen, W. J. Brammar
semanticscholar   +1 more source

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

Advanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong, Jae Jun Kang, Ki‐Myo Kim, Mi hyun lee, Misun Cha, Su Hee Kim, Ji‐Ung Park   +6 more
wiley   +1 more source

Urine‐Stable Aptamer‐Conjugated Gold Nanorods for the Early Detection of High‐Grade Bladder Cancer Residual Disease

Advanced Healthcare Materials, EarlyView.
Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni, Silvia Tortorella, Alessandra Caliendo, Irene Locatelli, Alessia Di Coste, Erica Locatelli, Filippo Capancioni, Emanuela Bua, Simona Camorani, Andrea Salonia, Francesco Montorsi, Jithin Jose, Marco Moschini, Laura Cerchia, Mauro Comes Franchini, Massimo Alfano   +15 more
wiley   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source

Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells

Advanced Healthcare Materials, EarlyView.
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng, Yu Qian, Xinxin Xiao, Fengdi Gao, Guoqiang Ren, Cristian Pablo Pennisi   +5 more
wiley   +1 more source

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

Advanced Healthcare Materials, EarlyView.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez, Jenny E. Hernandez‐Davies, Aarti Jain, Lu Wang, Erwin Strahsburger, D. Huw Davies, Szu‐Wen Wang   +6 more
wiley   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Restriction Enzymes as a Target for DNA-Based Sensing and Structural Rearrangement

ACS Omega, 2018
Susan Buckhout-White, Chanel Person, Igor L. Medintz, Ellen R. Goldman   +3 more
doaj   +1 more source

Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay

, 2010
Jayati Roy Choudhury, Lu Rao, Ulrich Bierbach   +2 more
openalex   +2 more sources