Results 81 to 90 of about 2,453,331 (300)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Computation of Splicing Languages from DNA Splicing System Based on Sequences of Restriction Enzymes [PDF]

, 2019
In DNA splicing systems, restriction enzymes and ligases cleave and recombine DNA molecules based on the cleavage pattern of the restriction enzymes. The set of molecules resulting from the splicing system depicts a splicing language.
Nurul Izzaty Ismail, Wan Heng Fong, Nor Haniza Sarmin, Fong, W. H., Ismail, N. I., Sarmin, N. H.   +5 more
core   +1 more source

Restriction modification systems in archaea: A panoramic outlook

Heliyon
Restriction modification (RM) systems are one of the ubiquitous yet primitive defense responses employed by bacteria and archaea with the primary role of safeguarding themselves against invading bacteriophages.
Pallavi Gulati, Ashish Singh, Sandeep Patra, Shreyas Bhat, Anil Verma   +4 more
doaj   +1 more source

Genetic Analysis Using Partial Sequencing of Melanocortin 4 Receptor (MC4R) Gene in Bligon Goat

Media Peternakan, 2017
Melanocortin 4 Receptor gene is involved in sympathetic nerve activity, adrenal and thyroid functions, and media for leptin in regulating energy balance and homeostasis. The aim of this research was to perform genetic analysis of MC4R gene sequences from
Latifah Latifah, D. A. Priyadi, D. Maharani, Kustantinah Kustantinah, T. Hartatik   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes [PDF]

, 1981
Dreiseikelmann B, Wackernagel W. Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes. Journal of Bacteriology. 1981;147(1):
Dreiseikelmann, Brigitte, Wackernagel, Wilfried   +1 more
core  

A whole genome screen for HIV restriction factors [PDF]

, 2011
Background Upon cellular entry retroviruses must avoid innate restriction factors produced by the host cell. For human immunodeficiency virus (HIV) human restriction factors, APOBEC3 (apolipoprotein-B-mRNA-editing-enzyme), p21 and tetherin are well ...
Dittmar Matthias T, Borgdorff Viola, Matthias T Dittmar, Kelly M Cheney, Áine McKnight, Borgdorff, V, Liu, L, Beach, DH, Pade Corinna, Dreja, H, McKnight, A, Pade, C, Cheney, KM, Dreja Hanna, Nidia MM Oliveira, Bergin, A-MH, Bishop, CL, Bergin Ann-Marie H, Beach David H, Cheney Kelly M, Cleo L Bishop, Dittmar, MT, Bishop Cleo L, Liu Li, David H Beach, Hanna Dreja, Li Liu, Ann-Marie H Bergin, Oliveira, NMM, McKnight Áine, Oliveira Nidia MM, Viola Borgdorff, Corinna Pade   +32 more
core   +8 more sources

Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences.

PLoS ONE, 2019
Restriction enzymes recognize and bind to specific sequences on invading bacteriophage DNA. Like a key in a lock, these proteins require many contacts to specify the correct DNA sequence.
Thomas D Schneider, Vishnu Jejjala
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Inhibition of restriction enzyme's DNA sequence recognition by PUVA treatment [PDF]

Nucleic Acids Symposium Series, 2001
Applying various restriction enzymes on a specially designed 1.5 kb DNA fragment revealed that the inhibitory effects of PUVA treatment on restriction endonuclease activities are caused by recognition inhibition. In this study, Restriction enzymes which have a 5'-TpA sequence at the cleaving site (Kpn I, Xba I, Pme I, and Dra I), and non-cleaving site (
Hanawa, F., Okamoto, M., Towers, G.
openaire   +4 more sources