Results 121 to 130 of about 3,718,372 (390)

Characterization of the complete mitochondrial genome of Euspira gilva with phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2020
Here, we determined the complete mitogenome sequence of Euspira gilva (Littorinimorpha: Naticidae). The complete mitochondrial genome is circular and 16,119 bp in length, containing 13 protein-coding genes (PCGs), 2 ribosomal RNA genes, and 22 transfer ...
Zongxing Wang   +5 more
doaj   +1 more source

Surveying Saccharomyces genomes to identify functional elements by comparative DNA sequence analysis.

open access: yesGenome Research, 2001
Comparative sequence analysis has facilitated the discovery of protein coding genes and important functional sequences within proteins, but has been less useful for identifying functional sequence elements in nonprotein-coding DNA because the relatively ...
P. Cliften   +7 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

open access: yesGenome Research, 2001
The genomic organization of the human protocadherin alpha, beta, and gamma gene clusters (designated Pcdh alpha [gene symbol PCDHA], Pcdh beta [PCDHB], and Pcdh gamma [PCDHG]) is remarkably similar to that of immunoglobulin and T-cell receptor genes. The
Qiang Wu   +10 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

abc4pwm: affinity based clustering for position weight matrices in applications of DNA sequence analysis. [PDF]

open access: yesBMC Bioinformatics, 2022
Ali O   +5 more
europepmc   +1 more source

Analysis of human tumors and human malignant cell lines for BK virus-specific DNA sequences [PDF]

open access: green, 1978
William S.M. Wold   +5 more
openalex   +1 more source

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