Results 301 to 310 of about 3,843,395 (391)

Structural basis for genome-wide site-specific DNA recognition by Nuclear Factor IA. [PDF]

Nat Commun
Zhu C, Xiao D, Luo Z, Zhang J, Liu S, Wang Y, Chen X, Xiao H, Li X, Tang J, Fang X, Shen J, Song H.   +12 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

CRISPR/Cas12a-RCA enables ultrasensitive detection of circulating free DNA for noninvasive diagnosis of echinococcosis. [PDF]

PLoS Negl Trop Dis
Ma J, Zhang Y, Li Z, Liu L, A J, Liang R, Cao C, Zhou J, Cheng P, Li Y, Li Z, Ma L, Jiang L, A X.   +13 more
europepmc   +1 more source

NMR-based conformational analysis of DNA G-quadruplex guides mapping essential structure-function relationship in protein chaperoning.

Phys Chem Chem Phys
Negi D, Huang Z, Son A, Sathyamoorthy B, Horowitz S.   +4 more
europepmc   +1 more source

A structure-guided approach to noncoding variant evaluation for transcription factor binding using AlphaFold 3. [PDF]

Nucleic Acids Res
Gerasimavicius L, Biddie SC, Marsh JA.
europepmc   +1 more source

Draft genome sequence of <i>Paenibacillus</i> sp. M.A.Huq-81 isolated from the soil sample of a pine garden located in Anseong, South Korea. [PDF]

Microbiol Resour Announc
Huq MA, Park J-W, Rahman MS.
europepmc   +1 more source

Versatile genome editing using Type I-E CRISPR-Cas3 in rice. [PDF]

Plant Cell Physiol
Saika H, Hara N, Yasumoto S, Muranaka T, Yoshimi K, Mashimo T, Toki S.   +6 more
europepmc   +1 more source

Zero-shot deep learning for the annotation of unknown eDNA sequences using co-occurrences and phylogenetic embeddings. [PDF]

PLoS Comput Biol
Stalder S, Sanchez T, Volpi M, Manel S, Mouillot D, Auber A, Bruno M, Marques V, Albouy C, Pellissier L.   +9 more
europepmc   +1 more source

Protocol for integrative analysis of transcription factor-nucleosome interactions using SeEN-seq and cryo-EM structure determination. [PDF]

STAR Protoc
Kobayashi W, Michael AK, Ruangroengkulrith S, Kümmecke M, Tachibana K.   +4 more
europepmc   +1 more source