Results 251 to 260 of about 34,995 (285)
Some of the next articles are maybe not open access.
DNA Shuffling for Whole Cell Engineering
2003Pasteur patented the use of whole microbial cells in fermentation in the latter part of the nineteenth century. However, there are much earlier references to microbial fermentations, dating back to alcohol fermentation thousands of years ago. Although more recent times have seen the introduction of many novel processes.
Steve del Cardayre, Keith Powell
openaire +1 more source
The analysis of DNA shuffling by nMDS
2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW), 2011DNA shuffling is widely used for optimizing complex properties contained within DNA and proteins. However, success rate of it is deeply dependent upon which pair of DNAs is employed for DNA shuffling. In this paper, we have used non-metric multidimensional scaling (nMDS) to select best pair of DNAs for it.
Ryota Doi, Y. Taguchi
openaire +1 more source
DNA Shuffling and Screening Strategies for Improving Vaccine Efficacy
DNA and Cell Biology, 2005The efficacy of vaccines can be improved by increasing their immunogenicity, broadening their crossprotective range, as well as by developing immunomodulators that can be coadministered with the vaccine antigen. One technology that can be applied to each of these aspects of vaccine development is MolecularBreeding directed molecular evolution ...
Christopher P, Locher +3 more
openaire +2 more sources
Molecular dissection of human Argonaute proteins by DNA shuffling
Nature Structural & Molecular Biology, 2013A paramount task in RNA interference research is to decipher the complex biology of cellular effectors, exemplified in humans by four pleiotropic Argonaute proteins (Ago1-Ago4). Here, we exploited DNA family shuffling, a molecular evolution technology, to generate chimeric Ago protein libraries for dissection of intricate phenotypes independently of ...
Nina, Schürmann +4 more
openaire +2 more sources
ShuffleAnalyzer: A Comprehensive Tool to Visualize DNA Shuffling
ACS Synthetic BiologyDNA shuffling is a powerful technique for generating synthetic DNA via recombination of homologous parental sequences. Resulting chimeras are often incorporated into complex libraries for functionality screenings that identify novel variants with improved characteristics.
Franz Schweiggert +4 more
openaire +2 more sources
Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly
DNA Shuffling and Family Shuffling for In Vitro Gene Evolution
2002Miho, Kikuchi, Shigeaki, Harayama
openaire +2 more sources
DNA Shuffling of Cytochromes P450 for Indigoid Pigment Production
2013DNA family shuffling is a powerful method of directed evolution applied for the generation of novel enzymes with the aim of improving their existing features or creating completely new enzyme properties. This method of evolution in vitro requires parental sequences containing a high level of sequence similarity, such as is found in family members of ...
openaire +3 more sources
Family Shuffling with Single-Stranded DNA
2003Wenjuan, Zha, Tongbo, Zhu, Huimin, Zhao
openaire +2 more sources