Results 71 to 80 of about 699,352 (277)
DNA Computation Based Approach for Enhanced Computing Power [PDF]
, 2011 DNA computing is a discipline that aims at harnessing individual molecules at the nano-scopic level for computational purposes. Computation with DNA molecules possesses an inherent interest for researchers in computers and biology.
Hameed, Kashif
core
Models and information-theoretic bounds for nanopore sequencing
, 2018 Nanopore sequencing is an emerging new technology for sequencing DNA, which can read long fragments of DNA (~50,000 bases) in contrast to most current short-read sequencing technologies which can only read hundreds of bases. While nanopore sequencers can
Diggavi, Suhas +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Optimizing Sequencing Coverage Depth in DNA Storage: Insights from DNA Storage Data
2025 IEEE International Symposium on Information Theory (ISIT)DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding digital data, minimizing DNA coverage depth helps lower both costs and system latency.
Cao, Ruiying, Chen, Xin
openaire +2 more sources
Asymmetric Lee Distance Codes for DNA-Based Storage [PDF]
, 2016 We consider a new family of codes, termed asymmetric Lee distance codes, that arise in the design and implementation of DNA-based storage systems and systems with parallel string transmission protocols.
Gabrys, Ryan +2 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
DNA Storage: A Promising Large Scale Archival Storage?
, 2022 Deoxyribonucleic Acid (DNA), with its high density and long durability, is a promising storage medium for long-term archival storage and has attracted much attention. Several studies have verified the feasibility of using DNA for archival storage with a small amount of data.
Wei, Yixun, Li, Bingzhe, Du, David H. C.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Mobile and Self‐Sustained Data Storage in an Extremophile Genomic DNA
Advanced Science, 2023 DNA has been pursued as a novel biomaterial for digital data storage. While large‐scale data storage and random access have been achieved in DNA oligonucleotide pools, repeated data accessing requires constant data replenishment, and these ...
Fajia Sun +6 more
doaj +1 more source
An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples. [PDF]
, 2015 BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive ...
Adams, Matthew +16 more
core +2 more sources