Microbial Primer: Bacterial DNA supercoiling. [PDF]
Dorman CJ.
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Direct trapping of the transport-segment DNA by the central domain of type IIA topoisomerases. [PDF]
Xin Y +6 more
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Topoisomerases as Targets for Novel Drug Discovery. [PDF]
Perdih A.
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Mechanistic basis for relaxation of DNA supercoils by human topoisomerase IIIα-RMI1-RMI2. [PDF]
Spakman D +6 more
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Investigation of effects of ellipticine derivatives on human DNA topoisomerases enzymes
DNA topoizomerazlar replikasyon, transkripsiyon, rekombinasyon gibi hayati öneme sahip hücresel basamaklarda fonksiyonlara sahip olan enzimlerdir. Bu enzimler, DNA üzerinde geçici kırıklar oluşturarak molekülün kimyasal yapısını etkilemeden üç boyutlu ...
Kuşkucu, Melis
core
Differential roles of type I topoisomerases in regulating HPV pathogenesis. [PDF]
Vats A, Templeton CW, Laimins L.
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Identification of a <i>TOP3A</i> genetic variant as a novel biomarker for sensitivity to doxorubicin. [PDF]
Takacova T, Schirmer MA.
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Gyrase and Topoisomerase IV as Antibacterial Targets for Gepotidacin and Zoliflodacin: Teaching Old Enzymes New Tricks. [PDF]
Osheroff N.
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Enzyme-DNA Interactions Affect the Catalytic Inhibition of Mycobacterial Gyrases by Antibacterial Drugs. [PDF]
Armenia JF, Osheroff N.
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Processing of DNA Topoisomerase II-DNA-Protein Crosslinks Associated With Anticancer Drugs. [PDF]
Sakasai R, Iwabuchi K.
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