Unraveling the Role of Topoisomerase 3β (TOP3B) in mRNA Translation and Human Disease. [PDF]
Warrick JE, Kearse MG.
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Topo IV is required to allow replisomes to converge and complete replication on the chromosome. [PDF]
Mokhtari PD +4 more
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Spatial Chromatin Organization Across the Cell Cycle: Insights from Auxin-Inducible Protein Depletion. [PDF]
Nurislamov A, Yunusova A.
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Spo11: from topoisomerase VI to meiotic recombination initiator. [PDF]
Harper JA, Brown GGB, Neale MJ.
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A Review of Natural and Synthetic Chalcones as Anticancer Agents Targeting Topoisomerase Enzymes. [PDF]
Toublet FX, Laurent A, Pouget C.
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Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA
Type II DNA topoisomerase enzymes (TOP2) catalyze topological changes by strand passage reactions. They involve passing one intact double stranded DNA duplex through a transient enzyme-bridged break in another (gated helix) followed by ligation of the break by TOP2.
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Cohesin forms fountains at active enhancers in C. elegans. [PDF]
Lüthi BN +12 more
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Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor. [PDF]
van Schaik T +13 more
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Substituted Triazole-3,5-Diamine Compounds as Novel Human Topoisomerase III Beta Inhibitors. [PDF]
Mamun Y +8 more
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Conformations of the three gates in Saccharomyces cerevisiae topoisomerase II and their response to DNA, nucleotide, and etoposide. [PDF]
Stelljes JT, Klostermeier D.
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