Results 201 to 210 of about 16,951 (259)

Molecular resistance mechanisms to newly approved antibiotics (2017-2025) in WHO priority pathogens. [PDF]

Front Microbiol
Sartori M, Toppo S, Lavezzo E.
europepmc   +1 more source

DNA Decatenation Catalyzed by Bacterial Topoisomerase IV. [PDF]

Methods Mol Biol
Armenia JF, Osheroff N.
europepmc   +1 more source

Camptothecin, a topoisomerase I inhibitor, impedes productive herpes simplex virus type 1 infection. [PDF]

J Virol
Heath JR, Lloyd AE, Kulinski RM, Fromuth DP, Dembowski JA.   +4 more
europepmc   +1 more source

DNA TOP1α coordinates anther morphogenesis and fertility through gene regulatory networks in arabidopsis. [PDF]

Sci Rep
Elesawi IE, Zhang N, Hashem AM, Yao L, Abdullah HM, Maher M, Alshaya DS, Al Aboud NM, ALshamrani SM, Shehata WF, Hassanin AA, El-Moneim DA, Chen C.   +12 more
europepmc   +1 more source

How Do Gepotidacin and Zoliflodacin Stabilize DNA-Cleavage Complexes with Bacterial Type IIA Topoisomerases? 2. A Single Moving Metal Mechanism. [PDF]

Int J Mol Sci
Nicholls RA, Morgan H, Warren AJ, Ward SE, Long F, Murshudov GN, Sutormin D, Bax BD.   +7 more
europepmc   +1 more source

Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against <i>Neisseria gonorrhoeae</i> Gyrase and Topoisomerase IV in Cells and In Vitro. [PDF]

ACS Infect Dis
Oviatt AA, Collins JA, Mann CA, Huang J, Mattern K, Chan PF, Osheroff N.   +6 more
europepmc   +1 more source

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Type II DNA topoisomerases in trypanosomatid and apicomplexan parasites

Acta Tropica, 2022
Diseases caused by trypanosomatid parasites have no commercially available vaccines for human application. Treatment modalities completely rely on chemotherapeutics strategies that often exhibit clinical drawbacks, like host toxicity, side effects and treatment failure for drug resistance.
Somenath Roy Chowdhury, Arpita Bhoumik, Vivek Kumar Gupta, Hemanta K. Majumder   +3 more
openaire   +2 more sources

Phylogenomics of type II DNA topoisomerases

BioEssays, 2003
AbstractType II DNA topoisomerases (Topo II) are essential enzymes implicated in key nuclear processes. The recent discovery of a novel kind of Topo II (DNA topoisomerase VI) in Archaea led to a division of these enzymes into two non‐homologous families, (Topo IIA and Topo IIB) and to the identification of the eukaryotic protein that initiates meiotic ...
Danièle, Gadelle, Jonathan, Filée, Cyril, Buhler, Patrick, Forterre   +3 more
openaire   +2 more sources