Results 121 to 130 of about 2,477,957 (291)

DNA Transformation

Stanley Cohen and Herbert Boyer's historic experiment used techniques to cut and paste DNA to create the first custom-made organism containing recombined or 'recombinant' DNA.

core   +2 more sources

DNA uptake from a laboratory environment drives unexpected adaptation of a thermophile to a minor medium component. [PDF]

ISME Commun, 2023
Zeldes B, Poehlein A, Jain S, Baum C, Daniel R, Müller V, Basen M.   +6 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Classified for SoA 2015-16

, 2015
Vacancy notification for School of Architecture A.Y.
DNA
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

DNA Origami Uptake in Y‐79 Retinoblastoma Cells Driven by Oligolysine Coating

Small Structures
DNA origami nanoparticles (DONs) are attractive nanocarriers of controllable size, shape, and addressability that have potential for treating eye diseases by overcoming ocular barriers. However, suboptimal physiological stability and poor cell uptake due
Anna Klose, Zahra Gounani, Sergei Raik, Artturi Koivuniemi, Sonja Korhonen, Mika Reinisalo, Tatu Lajunen, Veikko Linko, Timo Laaksonen   +8 more
doaj   +1 more source

"Take It or Leave It"-Factors Regulating Competence Development and DNA Uptake in Campylobacter jejuni. [PDF]

Int J Mol Sci, 2021
Golz JC, Stingl K.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Tad pilus-mediated twitching motility is essential for DNA uptake and survival of Liberibacters. [PDF]

PLoS One, 2021
Cai L, Jain M, Sena-Vélez M, Jones KM, Fleites LA, Heck M, Gabriel DW.   +6 more
europepmc   +1 more source