Journal of Extracellular Vesicles, 2014 The induction of an active immune response to control or eliminate tumours is still an unfulfilled challenge. We focused on plasmid DNA vaccines using an innovative approach whereby the antigen is expressed in association with extracellular vesicles (EVs)
C. Sedlik +9 more
semanticscholar +1 more source
DNA Vaccines for Emerging Infectious Diseases: What If?
Emerging Infectious Diseases, 1996 A novel and powerful method for vaccine research, colloquially known as DNA vaccines, involves the deliberate introduction into tissues of a DNA plasmid carrying an antigen-coding gene that transfects cells in vivo and results in an immune response.
Robert G. Whalen
doaj +1 more source
DNA vaccines against influenza.
Acta Biochimica Polonica, 2014 Genetic vaccine technology has been considerably developed within the last two decades. This cost effective and promising strategy can be applied for therapy of cancers and for curing allergy, chronic and infectious diseases, such as a seasonal and ...
A. Stachyra, A. Góra-Sochacka, A. Sirko
semanticscholar +1 more source
Contemporary outbreaks of different avipoxviruses in Humboldt penguins of wild animal park Planckendael and in chickens of commercial poultry farms in Belgium [PDF]
, 2017 In the present study, the first outbreak of a penguinpox virus (PPV) in Humboldt penguins (Spheniscus humboldd) and four outbreaks of fowlpox virus (FPV) in layer chickens are reported.
Avalakuppa Papi Reddy, Vishwanatha Reddy +3 more
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A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
, 2010 Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe +14 more
core +2 more sources
Trial watch: DNA-based vaccines for oncological indications
OncoImmunology, 2017 DNA-based vaccination is a promising approach to cancer immunotherapy. DNA-based vaccines specific for tumor-associated antigens (TAAs) are indeed relatively simple to produce, cost-efficient and well tolerated.
Stefano Pierini +7 more
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Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. [PDF]
, 2019 BackgroundAlzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline.
Agadjanyan, Michael G +14 more
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The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]
, 2016 Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA +4 more
core +7 more sources
Oral human papillomavirus (HPV) infection in men who have sex with men: prevalence and lack of anogenital concordance. [PDF]
, 2015 To estimate the prevalence of oral detectable human papillomavirus (HPV) DNA in HIV-negative men who have sex with men (MSM) attending a sexual health clinic in London and concordance with anogenital HPV infection.
Beddows, S +8 more
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