Results 1 to 10 of about 195,093 (153)
Human Vaccines & Immunotherapeutics, 2017 A major advantage of DNA vaccination is the ability to induce both humoral and cellular immune responses. DNA vaccines are currently used in veterinary medicine, but have not achieved widespread acceptance for use in humans due to their low ...
John J. Suschak +2 more
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Lipid nanoparticle-encapsulated DNA vaccine induces balanced antibody and T-cell responses in pigs with maternally derived antibodies [PDF]
Journal of VirologyMaternally derived antibodies (MDAs) play a vital role in protecting neonates from infectious diseases, but their presence at the time of vaccination can interfere with vaccine-induced immune responses, thereby reducing vaccine effectiveness.
Danh C. Lai +4 more
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Polyethylenimine-Conjugated Au-NPs as an Efficient Vehicle for in vitro and in vivo DNA Vaccine Delivery [PDF]
International Journal of NanomedicineAras Kartouzian,1 Alexandra Heiz,1 Kamyar Shameli,2,* Hassan Moeini3,* 1Catalysis Research Center, School of Natural Sciences, Technical University of Munich, Munich, Germany; 2Institute of Virology, School of Medicine, Technical University of ...
Kartouzian A +3 more
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Induction of specific immune responses in inoculated mice by a eukaryotic plasmid expressing the G1 epitope of bovine ephemeral fever virus [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 Objective Bovine ephemeral fever (BEF) is an arthropod-borne viral disease of cattle and water buffalos which causes considerable economic and commercial losses in the cattle industry.
Reza Pasandideh +2 more
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Japanese Journal of Pharmacology, 2000 DNA vaccination or genetic immunization is a rapidly developing technology that offers new approaches for the prevention and therapy of disease. Regarding the inoculation method of DNA vaccine, we recommend the gene gun delivery system, which is a highly reliable method compared to intramuscular inoculation. DNA vaccines could have potential advantages
Koide, Yukio +3 more
+8 more sources
Current Biology, 1998 DNA vaccination against infectious diseases has created a new field of applied molecular immunology. cDNAs for 'protective' protein epitopes can be inserted into vectors containing strong mammalian promoters for high expression. Here we discuss the mechanisms of DNA vaccination and the successful and sometimes unsuccessful applications of DNA ...
W C, Lai, M, Bennett
openaire +4 more sources
Expert Opinion on Emerging Drugs, 2003 There is increasing recognition that the unique antigenicities of the different stages of the Plasmodium spp. life cycle, the requirement for distinct immune mechanisms targeting these different stages, the immense allelic variation of parasites in the field, and the genetic heterogeneity of the target population pose enormous obstacles to the ...
Hedstrom, Richard C., Doolan, Denise L.
+10 more sources
DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Helicobacter pylori is one of the most prevalent human infectious agents that is directly involved in various upper digestive tract diseases. Although antibiotics-based therapy and proton pump inhibitors eradicate the bacteria mostly, their
Hossein Ansari +2 more
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Poultry Science, 2020 To evaluate the ability of inulin to enhance the immune response of a ptfA gene DNA vaccine for avian Pasteurella multocida, inulin was added as an adjuvant to the ptfA-DNA vaccine, obtaining an inulin-adjuvant DNA vaccine.
Q. Gong, Y.G. Peng, M.F. Niu, C.L. Qin
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Drug Delivery, 2021 We developed a biocompatible splenic vector for a DNA vaccine against melanoma. The splenic vector is a ternary complex composed of plasmid DNA (pDNA), biodegradable dendrigraft poly-L-lysine (DGL), and γ-polyglutamic acid (γ-PGA), the selective uptake ...
Yukinobu Kodama +11 more
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