Tumor Tropism of DNA Viruses for Oncolytic Virotherapy [PDF]
Viruses, 2023 Oncolytic viruses (OVs) have emerged as one of the most promising cancer immunotherapy agents that selectively target and kill cancer cells while sparing normal cells. OVs are from diverse families of viruses and can possess either a DNA or an RNA genome.
Junior A. Enow +2 more
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Frontiers in Microbiology, 2015 DNA viruses undertake their replication within the cell nucleus, and therefore they must first deliver their genome into the nucleus of their host cells. Thus, trafficking across the nuclear envelope is at the basis of DNA virus infections.
Nikta eFay, Nelly ePante
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Codon usage of human DNA viruses and its similarity to certain host genes [PDF]
Scientific ReportsCodon usages of DNA viruses had previously been shown to associate with their genome size. Codon usage of various human DNA viruses was compared to those of human genes to further understand viral codon usage and its roles in viral-host interaction ...
Thanyaporn Sirihongthong +4 more
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Pervasive Chimerism in the Replication-Associated Proteins of Uncultured Single-Stranded DNA Viruses
Viruses, 2018 Numerous metagenomic studies have uncovered a remarkable diversity of circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses, the majority of which are uncultured and unclassified. Unlike capsid proteins, the Reps show
Darius Kazlauskas +2 more
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Replication Compartments of DNA Viruses in the Nucleus: Location, Location, Location
Viruses, 2020 DNA viruses that replicate in the nucleus encompass a range of ubiquitous and clinically important viruses, from acute pathogens to persistent tumor viruses.
Matthew Charman, Matthew D. Weitzman
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Virus discovery in all three major lineages of terrestrial arthropods highlights the diversity of single-stranded DNA viruses associated with invertebrates [PDF]
PeerJ, 2018 Viruses encoding a replication-associated protein (Rep) within a covalently closed, single-stranded (ss)DNA genome are among the smallest viruses known to infect eukaryotic organisms, including economically valuable agricultural crops and livestock ...
Karyna Rosario +10 more
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Identification and characterization of novel CRESS-DNA viruses in the human respiratory tract [PDF]
Virology JournalCRESS-DNA viruses are small, circular, single-stranded DNA viruses that have been identified in diverse environments and hosts, including vertebrates, invertebrates, and environmental samples.
Huanyan Zhang +6 more
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Sensing Viruses by Mechanical Tension of DNA in Responsive Hydrogels
Physical Review X, 2014 The rapid worldwide spread of severe viral infections, often involving novel mutations of viruses, poses major challenges to our health-care systems. This means that tools that can efficiently and specifically diagnose viruses are much needed.
Jaeoh Shin +2 more
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Interactions between Autophagy and DNA Viruses
Viruses, 2019 Autophagy is a catabolic biological process in the body. By targeting exogenous microorganisms and aged intracellular proteins and organelles and sending them to the lysosome for phagocytosis and degradation, autophagy contributes to energy recycling ...
Hai-chang Yin +5 more
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Towards quantitative viromics for both double-stranded and single-stranded DNA viruses [PDF]
PeerJ, 2016 Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA) viral genomes ...
Simon Roux +8 more
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