Results 151 to 160 of about 4,207,382 (399)
Virus evolution : the emergence of new ideas (and re-emergence of old ones)
, 2006 Reputed intractable, the question of the origin of viruses has long been neglected. In the modern literature 'Virus evolution' has come to refer to study more akin to population genetics, such as the world-wide scrutiny on new polymorphisms appearing ...
Claverie, Jean-Michel
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
A DNA Plasmid-Based Approach for Efficient Synthesis of Sacbrood Virus Infectious Clones within Host Cells [PDF]
, 2023 Dandan Yue +6 more
openalex +1 more source
Viral modulation of interferon (IFN) responses to african swine fever virus (ASFV) [PDF]
, 2011 Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A imunidade inata constitui a primeira resposta dada por um hospedeiro quando atacado por agentes patogénicos. A resposta imune baseia-se em genes
Costa, Emanuel Nery de Oliveira Quartin, 1986-
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat. [PDF]
, 1991 Neonatal CxD2 (Rmcfr) and Balb/c (Rmcfs) mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibited approximately equivalent time course and pathology for disease.
Brightman, BK, Fan, H, Li, QX, Trepp, DJ
core
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Soil Viruses: A New Hope. [PDF]
, 2019 As abundant members of microbial communities, viruses impact microbial mortality, carbon and nutrient cycling, and food web dynamics. Although most of our information about viral communities comes from marine systems, evidence is mounting to suggest that
Emerson, Joanne B
core
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Viruses are a key regulator of the microbial carbon cycle in the deep-sea biosphere
Environmental Science and EcotechnologyThe marine biosphere profoundly influences atmospheric chemistry and climate through its carbon cycle. Viruses, the most abundant and diverse entities in marine ecosystems, significantly shape global carbon dynamics by infecting microbes and altering ...
Xinyi Zhang +3 more
doaj +1 more source