Results 201 to 210 of about 375,593 (258)

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Diverse Small Circular DNA Viruses Identified in an American Wigeon Fecal Sample. [PDF]

Microorganisms
Olivo D, Khalifeh A, Custer JM, Kraberger S, Varsani A.   +4 more
europepmc   +1 more source

Integrase-associated niche differentiation of endogenous large DNA viruses in crustaceans. [PDF]

Microbiol Spectr
Kawato S, Nozaki R, Kondo H, Hirono I.
europepmc   +1 more source

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DNA and the RNA viruses

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1971
Abstract Over the past decade our laboratory has worked intensively on the molecular details of RNA replication using the RNA bacteriophages as a model system. About a year and a half ago, I decided that the time had arrived for us to turn our accumulated technical armament on RNA replication to a problem of more immediate relevance ...
openaire   +2 more sources

Evasion of apoptosis by DNA viruses

Immunology & Cell Biology, 1996
Summary.Apoptosis is a form of cell death distinct from necrosis which plays an important role in processes such as homoeostasis and the elimination of damaged cells. It can be triggered by a variety of stimuli including DNA damage and cytotoxic T lymphocyte activity,1 both of which may be induced in the course of a viral infection.
S, Cuff, J, Ruby
openaire   +2 more sources

Physical Chemistry of DNA Viruses

Annual Review of Physical Chemistry, 2009
The relative simplicity of viruses makes it possible to apply generic physical approaches to the understanding of their structure and function. We focus here on viruses that have double-stranded (ds)DNA genomes that are enclosed in a protein container called the capsid.
Charles M, Knobler, William M, Gelbart
openaire   +2 more sources

DNA viruses and human cancer

Cancer Letters, 1988
This review examines some of the evidence which aetiologically implicates various DNA viruses (primarily papillomavirus, hepatitis B virus and Epstein-Barr virus) in certain human cancers (cervical carcinoma, primary liver cell carcinoma, Burkitt's lymphoma and nasopharyngeal carcinoma, respectively).
S J, Fey, P M, Larsen
openaire   +2 more sources

DNA Vaccines for Bacteria and Viruses

1996
DNA vaccines are nonreplicating plasmids encoding genes from pathogens. The antigenic proteins are thus expressed in the cells of the vaccinated host and result in the generation of both antibody and cell-mediated immune responses. The ability to generate proteins with native conformation contrasts with certain recombinant protein or inactivated viral ...
J B, Ulmer, R R, Deck, A, Yawman, A, Friedman, C, Dewitt, D, Martinez, D L, Montgomery, J J, Donnelly, M A, Liu   +8 more
openaire   +2 more sources