Results 91 to 100 of about 21,302 (228)

Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms

Therapeutic Advances in Neurological Disorders
Background: Ischemic stroke or transient ischemic attack (TIA) occurs in 1.4% of patients with atrial fibrillation (AF) per year despite treatment with direct oral anticoagulants (DOACs).
Marcus Rust, Merve Gözalan, Omid Nikoubashman, Martin Wiesmann, Matthias Imöhl, Jörg B. Schulz, Arno Reich, João Pinho   +7 more
doaj   +1 more source

Viscoelastic monitoring of direct oral anticoagulants (DOAC): Viscoeslastic monitoring of DOAC

Blood Transfusion
The management of procedures at risk of major or critical bleeding in patients treated with direct oral anticoagulants (DOAC) is challenging, making urgent monitoring to detect and quantify residual effects, optimal for accurate clinical decision making.
Mora, Lidia, Pons-Pellicé, Laura, Quintana-Díaz, Manuel   +2 more
openaire   +1 more source

Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel, Sabrina Bänsch, Laura Adam, Nathan Fekade, Alessandra Rünger, Tim Zell, Daniel J. Smit, Julian Kött, Isabel Heidrich, Michael Weichenthal, Selma Ugurel, Ulrike Leiter, Peter Mohr, Alexandra Geusau, Stephan Grabbe, Markus V. Heppt, Ralf Gutzmer, Jochen Utikal, Jan‐Christoph Simon, Sebastian Haferkamp, Laura Susok, Bastian Schilling, Edgar Dippel, Imke von Wasielewski, Jessica C. Hassel, Carola Berking, Stefan W. Schneider, Christoffer Gebhardt   +27 more
wiley   +1 more source

A new strategy for monitoring of direct oral anticoagulants in patients with cyanotic and complex congenital heart disease

International Journal of Cardiology Congenital Heart Disease
Background: Patients with congenital heart disease (CHD) often require an oral anticoagulation. Vitamin K antagonists (VKA) are the standard treatment, however, an increased hematocrit in patients with secondary erythrocytosis due to cyanosis complicates
Fabienne Dirbach, Eleni Goulouti, Judith Bouchardy, Magalie Ladouceur, Lorenzo Alberio, Tobias Rutz   +5 more
doaj   +1 more source

DOAC in COVID-19: Yes or No?

HemaSphere, 2020
of
R. Schutgens
semanticscholar   +1 more source

Is Routine Interruption of Direct Oral Anticoagulants Necessary during Colorectal Endoscopic Mucosal Resection and Hot Snare Polypectomy? A Multicenter Propensity‐Matched Study

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Colorectal endoscopic mucosal resection (EMR) and hot snare polypectomy (HSP) are high‐bleeding‐risk endoscopic procedures, and most clinical guidelines recommend stopping direct oral anticoagulants (DOACs) temporarily or switching to heparin‐bridging therapy (HBT). However, existing evidence is largely derived from cohorts
Yutaka Okagawa, Masanori Sato, Masahiro Hirakawa, Shogo Miura, Naotaka Hayasaka, Yusuke Tomita, Saki Ameda, Ginji Omori, Shutaro Oiwa, Akira Sakurada, Tomoyuki Abe, Shinya Minami, Tetsuya Sumiyoshi, Yasuhiro Nagaoka, Hiroyuki Hisai, Shinichi Katsuki, Kohichi Takada   +16 more
wiley   +1 more source

Pharmacist Use of a Population Management Dashboard for Safe Anticoagulant Prescribing: Evaluation of a Nationwide Implementation Effort

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Direct oral anticoagulants (DOACs) have complex dosing regimens and are often incorrectly prescribed. We evaluated a nationwide DOAC population management dashboard rollout whose purpose includes pharmacist review and correction of off‐label ...
Geoffrey D. Barnes, Charity Chen, Rob Holleman, Joshua Errickson, F. Jacob Seagull, Michael P. Dorsch, Arthur L. Allen, Patrick Spoutz, Jeremy B. Sussman   +8 more
doaj   +1 more source

Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick: An Expert Consensus Paper

Thrombosis and Haemostasis, 2023
J. Harenberg, R. Gosselin, A. Cuker, C. Becattini, I. Pabinger, Sven Poli, Jeffrey I. Weitz, W. Ageno, R. Bauersachs, I. Celap, Philip Choi, James Douketis, J. Douxfils, Ismail Elalamy, A. Falanga, J. Fareed, E. Favaloro, G. Gerotziafas, H. Herkner, S. Hetjens, L. Heubner, R. Klamroth, F. Langer, G. Lip, Brian Mac Grory, S. Margetić, A. Merrelaar, M. Pikta, T. Renné, Sam Schulman, M. Schwameis, D. Strbian, Alfonso J. Tafur, J. Vassart, F. Violi, J. Walenga, Christel Weiss   +36 more
semanticscholar   +1 more source

The DOAC‐FRAIL Study—Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are prescribed using fixed dosing regimens, despite limited evidence on their pharmacokinetic behavior in nursing home residents. Participants and Setting One hundred nursing home residents are receiving apixaban, rivaroxaban, dabigatran, or edoxaban in multiple long‐term care facilities in the ...
Irme S. Franssen, Melanie J. de Jong, Lars Visseren, Daan Teerds, Dave Hellenbrand, Yvonne Henskens, Henri Spronk, Daisy J. A. Janssen, Dionne C. W. Braeken, Sander M. J. van Kuijk, Kristien Winckers, Fabienne J. H. Magdelijns   +11 more
wiley   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source