Results 91 to 100 of about 15,919 (234)

Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms

Therapeutic Advances in Neurological Disorders
Background: Ischemic stroke or transient ischemic attack (TIA) occurs in 1.4% of patients with atrial fibrillation (AF) per year despite treatment with direct oral anticoagulants (DOACs).
Marcus Rust, Merve Gözalan, Omid Nikoubashman, Martin Wiesmann, Matthias Imöhl, Jörg B. Schulz, Arno Reich, João Pinho   +7 more
doaj   +1 more source

Could direct-acting oral anticoagulant be a possible cause of delayed pseudoaneurysm? A case report

Turkish Journal of Vascular Surgery, 2023
Delayed iatrogenic pseudoaneurysm (IPA) is very rare. We aimed to present a case of delayed femoral IPA using apixaban, which developed four months after coronary intervention (PCI). A 75-year-old female patient who had PCI four months ago presented with
Nurkay Katrancioglu, Faruk Serhatlioglu
doaj  

Coagulation and heparin requirements during ablation in patients under oral anticoagulant drugs

Journal of Arrhythmia, 2020
Background Anticoagulation during catheter ablation should be closely monitored with activated clotting time (ACT). However vitamin K antagonists (VKA) or direct oral anticoagulant drugs (DOAC) may act differently on ACT and on heparin needs.
Philippe Maury, Slimane Belaid, Agnès Ribes, Quentin Voglimacci‐Stephanopoli, Pierre Mondoly, Marie Blaye, Franck Mandel, Benjamin Monteil, Didier Carrié, Michel Galinier, Vanina Bongard, Anne Rollin, Sophie Voisin   +12 more
doaj   +1 more source

Variation in Anticoagulation Practice for Atrial High‐Rate Episodes: A Nationwide Cross‐Sectional Survey

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Atrial high‐rate episodes (AHRE) detected by cardiac implantable electronic devices (CIEDs) are associated with increased thromboembolic risk, yet their clinical significance and optimal anticoagulation strategy remain uncertain, particularly in the absence of electrocardiogram (ECG)‐confirmed atrial fibrillation.
Kyi Zin Thant, Ibrahim Antoun, Kaung Myat Thu, Riyaz Somani, Zakariyya Vali, G. Andre Ng, Mokhtar Ibrahim   +6 more
wiley   +1 more source

In a nutshell:Testing DOAC levels—when, why and what it means? [PDF]

Plasma direct oral anticoagulant (DOAC) levels are not routinely required for the majority of patients; however, they may provide valuable information in urgent clinical situations, including perioperative management, life- or limb-threatening bleeding ...
Thachil, Jecko, Roberts, Lara; id_orcid, Swan, Dawn   +2 more
core   +1 more source

Viscoelastic monitoring of direct oral anticoagulants (DOAC): Viscoeslastic monitoring of DOAC

Blood Transfusion
The management of procedures at risk of major or critical bleeding in patients treated with direct oral anticoagulants (DOAC) is challenging, making urgent monitoring to detect and quantify residual effects, optimal for accurate clinical decision making.
Mora, Lidia, Pons-Pellicé, Laura, Quintana-Díaz, Manuel   +2 more
openaire   +1 more source

The DOAC‐FRAIL Study—Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are prescribed using fixed dosing regimens, despite limited evidence on their pharmacokinetic behavior in nursing home residents. Participants and Setting One hundred nursing home residents are receiving apixaban, rivaroxaban, dabigatran, or edoxaban in multiple long‐term care facilities in the ...
Irme S. Franssen, Melanie J. de Jong, Lars Visseren, Daan Teerds, Dave Hellenbrand, Yvonne Henskens, Henri Spronk, Daisy J. A. Janssen, Dionne C. W. Braeken, Sander M. J. van Kuijk, Kristien Winckers, Fabienne J. H. Magdelijns   +11 more
wiley   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Management of Left Atrial Appendage Thrombi and Spontaneous Echo Contrast

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background To analyze the efficacy and safety of various anticoagulation strategies/regimen used for managing thrombus or spontaneous echo contrast in the left atrial appendage. Methods Thrombus or spontaneous echo contrast in the left atrial appendage was detected via transesophageal echocardiography in 83 patients, most often during a stroke
Timnou Bekouti Jean, Ravakiniaina Ranaivosoa Mialy, Ateba Ateba Nelly Stella, Tsague Kegni Hermann, Rambolarimanana Mansh, Ndobo Julia Valérie, Imbey Eheth Levy, Maury Philippe, Diawara Alpha, Roynard Jean Louis, Boombhi Jerome Hilaire   +10 more
wiley   +1 more source

Thrombolysis for Ischemic Stroke Despite Recent Ingestion of Direct Oral Anticoagulants – A Growing Dilemma Also in India

Annals of Indian Academy of Neurology
The administration of intravenous thrombolysis (IVT) for patients with acute ischemic stroke who have recently ingested direct oral anticoagulants (DOACs) presents a clinical challenge due to the perceived increased risk of intracranial hemorrhage (ICH).
Thomas R. Meinel, Naveen K. Paramasivan, Bijoy K. Menon, Urs Fischer, David J. Seiffge   +4 more
doaj   +1 more source