Results 81 to 90 of about 21,302 (228)

Cost‐effectiveness analysis of low‐dose direct oral anticoagulant (DOAC) for the prevention of cancer‐associated thrombosis in the United States

Cancer, 2020
Randomized controlled trials (RCTs) have demonstrated that low‐dose direct oral anticoagulants (DOACs), including rivaroxaban and apixaban, may help reduce the incidence of cancer‐associated venous thromboembolism (VTE).
Ang Li, J. Carlson, N. Kuderer, J. Schaefer, Shan Li, D. Garcia, A. Khorana, M. Carrier, G. Lyman   +8 more
semanticscholar   +1 more source

Design and Implementation of an Automated Interpretation Algorithm for Lupus Anticoagulant Functional Testing

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Lupus anticoagulant (LA) testing is essential, albeit complex, in the laboratory diagnosis of antiphospholipid syndrome (APS). Given the multi‐step workflow and the variability introduced by anticoagulant therapy, reagent differences, and interpretive approaches, result interpretation requires expert evaluation.
Chiara Novelli, Arianna Gatti, Flora Ierna, Elena Riccardi, Irene Cuppari   +4 more
wiley   +1 more source

Anti–factor Xa activity assays of direct‐acting oral anticoagulants during clinical care: An observational study

Research and Practice in Thrombosis and Haemostasis, 2021
Background Direct‐acting oral anticoagulants (DOACs) are increasingly used to prevent and treat thromboembolism. Although measurement of DOAC concentrations is not currently recommended as part of routine patient care, measurement of DOAC concentrations ...
Smrithi Sukumar, Melissa Cabero, Sharon Tiu, Margaret C. Fang, Scott C. Kogan, Janice B. Schwartz   +5 more
doaj   +1 more source

How I Investigate Borderline Prolonged aPTT: An Integrated Laboratory Approach to Mixing Studies and Factor Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Borderline prolongation of routine clotting assays—particularly the activated partial thromboplastin time (aPTT)—is a common interpretative challenge in laboratory hematology. These reproducible but mildly prolonged results often lie just beyond the upper reference limit and can trigger unnecessary follow‐up, delays, or misinterpretation ...
Nikolaos Androulakis, Eleni Nioti, Antonios Dilintas, Christina Kalpadakis   +3 more
wiley   +1 more source

Could direct-acting oral anticoagulant be a possible cause of delayed pseudoaneurysm? A case report

Turkish Journal of Vascular Surgery, 2023
Delayed iatrogenic pseudoaneurysm (IPA) is very rare. We aimed to present a case of delayed femoral IPA using apixaban, which developed four months after coronary intervention (PCI). A 75-year-old female patient who had PCI four months ago presented with
Nurkay Katrancioglu, Faruk Serhatlioglu
doaj  

Coagulation and heparin requirements during ablation in patients under oral anticoagulant drugs

Journal of Arrhythmia, 2020
Background Anticoagulation during catheter ablation should be closely monitored with activated clotting time (ACT). However vitamin K antagonists (VKA) or direct oral anticoagulant drugs (DOAC) may act differently on ACT and on heparin needs.
Philippe Maury, Slimane Belaid, Agnès Ribes, Quentin Voglimacci‐Stephanopoli, Pierre Mondoly, Marie Blaye, Franck Mandel, Benjamin Monteil, Didier Carrié, Michel Galinier, Vanina Bongard, Anne Rollin, Sophie Voisin   +12 more
doaj   +1 more source

Healthcare Professionals' perspectives on prescribing DOACs to frail older patients; The DOAC-FRAIL questionnaire

BMC Geriatrics
Abstract Background DOACs are increasingly prescribed for atrial fibrillation and venous thromboembolism due to their ease of use and lack of monitoring requirements. Prescribing DOACs to frail older patients remains challenging due to higher bleeding and thrombo-embolic risks, comorbidities, polypharmacy, and underrepresentation in ...
de Jong, M.J., Brys, A.DH., Braeken, D., Pisters, R., Janssen, D.JA., Altintas, S., Robben, S.HM., Nicolai, S., Eurlings, C., Zwietering, A., De Jonghe, M., Vaes, B., De Backer, T., Grymonprez, M., Joosten, H., ten Cate, H., Winckers, K., Magdelijns, F.JH.   +17 more
openaire   +2 more sources

Zero‐Contrast Versus Contrast‐Guided Left Atrial Appendage Occlusion: A Comparative Analysis of Procedural and Long‐Term Outcomes

Journal of Cardiovascular Electrophysiology, EarlyView.
Zero‐contrast left atrial appendage occlusion yielded high procedural success and similar periprocedural adverse event rates compared to the contrast‐guided approach. At 45‐day follow‐up, successful LAA closure (defined as peri‐device leak ≤ 5 mm) and device‐related thrombus rates were similar.
Joe Demian, Andrew LaCombe, Arwa Younis, Mohamed Kanj, Walid I. Saliba, Pasquale Santangeli, Chadi Tabaja, Ioan Liuba, Bryan Baranowski, Tyler L. Taigen, Mandeep Bhargava, Oussama M. Wazni, Ayman A. Hussein   +12 more
wiley   +1 more source

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

Journal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür, Emin Koyun, Gülşen Genç Tapar, Kayıhan Karaman, Metin Karayakali, Ataç Çelik, Uğur Kulu, Yasin Taşkin   +7 more
wiley   +1 more source

Early Bleeding Risk After DOAC Initiation With Concomitant Amiodarone in Older Adults With Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Amiodarone is frequently co‐prescribed with direct oral anticoagulants (DOACs) in atrial fibrillation (AF), but its impact on early bleeding risk after DOAC initiation in older adults remains uncertain. We evaluated short‐term safety outcomes associated with concomitant amiodarone use at the time of DOAC initiation.
Isadora D. Guarino, Saman Nazarian
wiley   +1 more source