Results 21 to 30 of about 21,302 (228)

Adverse Events of DOACs in Children

Frontiers in Pediatrics, 2022
Venous thromboembolism (VTE) has an increasing rate of significance in pediatric patients. The currently standardized anticoagulants (unfractionated heparin, low molecular weight heparin and vitamin K antagonists) and their dose regimens were not comprehensively trialed in pediatric patients.
Alessandra Bosch, Manuela Albisetti, Manuela Albisetti   +2 more
openaire   +3 more sources

Assessment of DOAC in GEriatrics ( Adage Study): Rivaroxaban/Apixaban Concentrations and Thrombin Generation Profiles in NVAF Very Elderly Patients

Thrombosis and Haemostasis, 2022
Background  Although a growing number of very elderly patients with atrial fibrillation (AF), multiple conditions, and polypharmacy receive direct oral anticoagulants (DOACs), few studies specifically investigated both apixaban/rivaroxaban ...
Geoffrey Foulon-Pinto, C. Lafuente-Lafuente, Georges Jourdi, J. L. Guen, Fatoumata Tall, E. Puymirat, M. Delrue, Léa Rivière, F. Ketz, I. Gouin-Thibault, F. Mullier, P. Gaussem, É. Pautas, T. Lecompte, E. Curis, V. Siguret   +15 more
semanticscholar   +1 more source

Performance of a Qualitative Point-of-Care Strip Test to Detect DOAC Exposure at the Emergency Department: A Cohort-Type Cross-Sectional Diagnostic Accuracy Study

Thrombosis and Haemostasis, 2022
An accurate point-of-care test for detecting effective anticoagulation by direct oral anticoagulants (DOACs) in emergencies is an unmet need. We investigated the accuracy of a urinary qualitative strip test (DOAC Dipstick) to detect relevant DOAC ...
A. Merrelaar, M. Bögl, Nina Buchtele, Marieke Merrelaar, H. Herkner, C. Schoergenhofer, J. Harenberg, J. Douxfils, R. Siriez, B. Jilma, A. Spiel, M. Schwameis   +11 more
semanticscholar   +1 more source

Optimization of DOAC management services in a centralized anticoagulation clinic

Research and Practice in Thrombosis and Haemostasis, 2022
In 2017, the Brigham and Women’s Hospital Anticoagulation Management Service (BWH AMS) expanded services to patients on direct oral anticoagulants (DOACs). We have since updated our DOAC management plan and adjusted the workflow of our clinic.
K. Sylvester, Alisia Chen, Andrea R. Lewin, J. Fanikos, S. Goldhaber, J. Connors   +5 more
semanticscholar   +1 more source

Management of Traumatic Brain Injury in Patients with DOAC Therapy–Are the “New” Oral Anticoagulants Really Safer?

Journal of Clinical Medicine, 2022
(1) Background: In recent years, “new” direct oral anticoagulants (DOAC) have gradually replaced other antithrombotic therapies. The international literature agrees on the increased mortality for traumatic brain injury (TBI) patients using vitamin K ...
A. Antoni, Lukas Wedrich, Martin Schauperl, L. Höchtl-Lee, I. Sigmund, M. Gregori, J. Leitgeb, E. Schwendenwein, S. Hajdu   +8 more
semanticscholar   +1 more source

Urine-based point-of-care testing for factor-Xa-inhibitors in acute ischemic stroke patients: a feasibility study

Frontiers in Neurology, 2023
IntroductionDirect oral anticoagulants (DOACs) have become widely used in clinical practice for preventing thromboembolic events. Point-of-care testing methods, particularly those based on urine samples, offer a promising approach for rapid and accurate ...
Thorsten R. Doeppner, Thorsten R. Doeppner, Thorsten R. Doeppner, Thorsten R. Doeppner, Linus Olbricht, Toska Maxhuni, Omar Alhaj Omar, Ulrich J. Sachs, Martin B. Juenemann, Hagen B. Huttner, Hagen B. Huttner, Hagen B. Huttner, Stefan T. Gerner, Stefan T. Gerner, Stefan T. Gerner   +14 more
doaj   +1 more source

Early antithrombotic post-discharge therapy using prophylactic DOAC or dipyridamole improves long-term survival and cardiovascular outcomes in hospitalized COVID-19 survivors

Frontiers in Cardiovascular Medicine, 2022
Introduction Cardiovascular events are common in COVID-19. While the use of anticoagulation during hospitalization has been established in current guidelines, recommendations regarding antithrombotic therapy in the post-discharge period are conflicting ...
L. Motloch, P. Jirak, M. Mirna, L. Fiedler, P. Davtyan, Irina A Lakman, D. Gareeva, A. Tyurin, R. Gumerov, S. Matskeplishvili, V. Pavlov, Benzhi Cai, Kristen Kopp, A. Topf, U. Hoppe, R. Pistulli, N. Zagidullin   +16 more
semanticscholar   +1 more source

The myths behind DOAC measurement: Analyses of prescribing information from different regulatory bodies and a call for harmonization

Journal of Thrombosis and Haemostasis, 2022
For more than a decade, US laboratories have failed to implement solutions to help their clinicians in managing complex situations or patients on direct oral anticoagulants (DOACs).
R. Gosselin, E. Favaloro, J. Douxfils
semanticscholar   +1 more source

Direct oral anticoagulant (DOAC) interference in hemostasis assays.

Hematology. American Society of Hematology. Education Program, 2021
Direct oral anticoagulants (DOACs) are a group of direct coagulation factor inhibitors including both direct thrombin inhibitors and direct factor Xa inhibitors.
K. Moser, K. Smock
semanticscholar   +1 more source

Direct oral anticoagulants increase bleeding risk after endoscopic sphincterotomy: a retrospective study

BMC Gastroenterology, 2021
Background Bleeding can be a serious adverse event of endoscopic sphincterotomy (EST). However, the risk of EST bleeding between direct oral anticoagulant (DOAC) users and those who received no antithrombotic agents has not been clarified.
Sakue Masuda, Kazuya Koizumi, Takashi Nishino, Tomohiko Tazawa, Karen Kimura, Junichi Tasaki, Chikamasa Ichita, Akiko Sasaki, Makoto Kako, Haruki Uojima, Ayumu Sugitani   +10 more
doaj   +1 more source