Results 21 to 30 of about 15,919 (234)

Prevention of thrombotic complications in patients in the postoperative period of total hip and knee arthroplasty: efficacy and safety

Евразийский Кардиологический Журнал, 2023
Thromboembolic complications (TEC) remain a significant problem in modern surgery, worsening the prognosis and reducing the effectiveness of the operation performed.
A. M. Ushanova, E. A. Okisheva, O. Iu. Mironova   +2 more
doaj   +1 more source

Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Thrombosis

Рациональная фармакотерапия в кардиологии, 2023
Aim. To investigate the effect of ABCB1 gene carriage and interdrug interactions on apixaban pharmacokinetics and clinical outcomes in patients with atrial fibrillation and deep vein thrombosis.Material and methods.
L. V. Fedina, I. N. Sychev, T. D. Rastvorova, E. V. Strigunkova, A. A. Kachanova, Z. A. Sozaeva, P. O. Bochkov, A. V. Vardanyan, K. B. Mirzayev, D. A. Sychev   +9 more
doaj   +1 more source

The Saudi Consensus for the Management of Cancer-Associated Thromboembolism: A Modified Delphi-Based Study

TH Open, 2023
Background Cancer is a well-known risk factor of preventable thromboembolic disease. This study aims to provide guidance on the prevention and management of cancer-associated thrombosis (CT) that tailors prophylactic and therapeutic options for medical ...
Mohammed Alsheef, Shouki Bazarbashi, Ashraf Warsi, Feras Alfraih, Abdualkreem Almoomen, Ahmed Osman, Tarek Owaidah   +6 more
doaj   +1 more source

A Model for Estimating the Risk of Gastrointestinal Bleeding for Patients on Oral Anticoagulants and Interacting Medications. [PDF]

Pharmacotherapy
ABSTRACT Introduction Pharmacodynamic drug–drug interactions (DDI) in patients receiving oral anticoagulants (OAC) may increase the risk of gastrointestinal bleeding (GIB). The purpose of this study was to develop and validate a GIB model for patients receiving OACs.
Gomez-Lumbreras A, Tawfik AG, Reese T, Witt DM, Del Fiol G, Malone DC.   +5 more
europepmc   +2 more sources

Safety of dabigatran in patients with atrial fibrillation and chronic kidney disease: pharmacokinetic and pharmacogenetic aspects

Медицинский совет, 2020
Background: despite well-studied safety profile of dabigatran its interactions with genetic polymorphism parameters are poorly understood, especially in patients with moderate chronic kidney disease (CKD).
A. I. Skripka, P. O. Bochkov, K. A. Akmalova, R. V. Shevchenko, P. M. Krupenin, V. V. Kogay, A. I. Listratov, A. S. Krainyaya, D. A. Napalkov, O. S. Gurinovich, A. A. Sokolova, V. V. Fomin, D. A. Sychev   +12 more
doaj   +1 more source

DOAC — nie u każdego i czasem w innych dawkach [PDF]

, 2022
Doustne bezpośrednie inhibitory krzepnięcia (DOAC) stosuje się w Europie już od ponad 10 lat. Jedną z ich istotnych zalet jest stosowanie w profilaktyce i leczeniu stałych dawek leków.
Musiał, Jacek
core   +1 more source

Adverse Events of DOACs in Children

Frontiers in Pediatrics, 2022
Venous thromboembolism (VTE) has an increasing rate of significance in pediatric patients. The currently standardized anticoagulants (unfractionated heparin, low molecular weight heparin and vitamin K antagonists) and their dose regimens were not comprehensively trialed in pediatric patients.
Alessandra Bosch, Manuela Albisetti, Manuela Albisetti   +2 more
openaire   +3 more sources

Direct oral anticoagulants (DOACs) [PDF]

Vascular Medicine, 2015
DOACs are a new group of blood-thinner medications that may have some advantages over warfarin. A health care provider will look at several different factors to help patients decide if a DOAC is a good choice. Patients taking DOACs should discuss medication changes, a plan for taking the DOAC before and after a surgery, and any bleeding side effects ...
Sara, Vazquez, Matthew T, Rondina
openaire   +2 more sources

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants

, 2023
Importance International guidelines recommend avoiding intravenous thrombolysis (IVT) in patients with ischemic stroke who have a recent intake of a direct oral anticoagulant (DOAC). Objective To determine the risk of symptomatic intracranial hemorrhage (
Scheitz, Jan F., Bae, Hee-Joon, Kaesmacher, Johannes, Gensicke, Henrik, Kim, Joon-Tae, Kim, Do Yeon, Kermer, Pawel, DOAC-IVT Writing Group for the International DOAC-IVT, TRISP, and CRCS-K-NIH Collaboration, Goganau, Ioana, Ringleb, Peter, Wilson, Duncan, Meinel, Thomas R.   +11 more
core   +1 more source

Urine-based point-of-care testing for factor-Xa-inhibitors in acute ischemic stroke patients: a feasibility study

Frontiers in Neurology, 2023
IntroductionDirect oral anticoagulants (DOACs) have become widely used in clinical practice for preventing thromboembolic events. Point-of-care testing methods, particularly those based on urine samples, offer a promising approach for rapid and accurate ...
Thorsten R. Doeppner, Thorsten R. Doeppner, Thorsten R. Doeppner, Thorsten R. Doeppner, Linus Olbricht, Toska Maxhuni, Omar Alhaj Omar, Ulrich J. Sachs, Martin B. Juenemann, Hagen B. Huttner, Hagen B. Huttner, Hagen B. Huttner, Stefan T. Gerner, Stefan T. Gerner, Stefan T. Gerner   +14 more
doaj   +1 more source