Results 121 to 130 of about 2,926,121 (366)
Review: The tale of the Finnish pig tail – how to manage non-docked pigs?
Animal, 2022 Tail biting is a serious behavioural problem in modern pig production, causing impaired animal welfare and economic losses. In most countries, the detrimental effects of tail biting are counteracted by docking pigs tails.
A. Valros
doaj
Multi-scale Iterative Refinement towards Robust and Versatile Molecular Docking [PDF]
arXiv, 2023 Molecular docking is a key computational tool utilized to predict the binding conformations of small molecules to protein targets, which is fundamental in the design of novel drugs. Despite recent advancements in geometric deep learning-based approaches leading to improvements in blind docking efficiency, these methods have encountered notable ...
arxiv
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
ffect of castration and docking of lambs on maintenance behaviour and cortisol level
Journal of Veterinary Medical Research, 2018 Thirty apparently healthy lambs with average weight and age of 5.8±0.5 kg and 15±1.6 days respectively were chosen in Sids Agricultural Research Station belonging to Animal Production Research Institute in Beni-Suef governorate to investigate the effect ...
H.H. Emeash +2 more
doaj
Human Vaccines & Immunotherapeutics, 2020 SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), is suspected to have been first contracted via animal-human interactions; it has further spread across the world by efficient human-to-human transmission.
Khan Sharun +10 more
doaj +1 more source
Targeting kinases with anilinopyrimidines: Discovery of N-phenyl-N'-[4-(pyrimidin-4-ylamino)phenyl]urea derivatives as selective inhibitors of class III receptor tyrosine kinase subfamily [PDF]
, 2015 Kinase inhibitors are attractive drugs/drug candidates for the treatment of cancer. The most recent literature has highlighted the importance of multi target kinase inhibitors, although a correct balance between specificity and non-specificity is ...
Chilin, Adriana +5 more
core +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 542-550, April 2025.Co‐crystallization crystallizes a protein with its ligand, resulting in protein–ligand complex crystals. In contrast, soaking introduces a ligand into preformed protein crystals, allowing it to bind. Both methods produce crystals for X‐ray diffraction, which generates diffraction patterns that are analyzed to determine the three‐dimensional structure ...
Barbora Kaščáková +4 more
wiley +1 more source
Why Pain Is Still a Welfare Issue for Farm Animals, and How Facial Expression Could Be the Answer
Agriculture, 2018 Pain is a sensory and emotional experience that significantly affects animal welfare and has negative impacts on the economics of farming. Pain is often associated with common production diseases such as lameness and mastitis, as well as introduced to ...
Krista Marie McLennan
doaj +1 more source
Animal Welfare Programs in Germany—An Empirical Study on the Attitudes of Pig Farmers
Agriculture, 2020 In Europe, there is ongoing social criticism of conventional pig farming and demands for higher farm animal welfare standards. This applies primarily to products from pig production, as consumers criticize, among other things, the animals’ housing ...
Sirkka Schukat +2 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Introduction Pain is considered an unpleasant sensory and emotional experience, being considered as one of the most important causes of human suffering. Computational chemistry associated with bioinformatics has stood out in the process of developing new
Davidson Barbosa Assis +10 more
semanticscholar +1 more source