Results 161 to 170 of about 2,926,121 (366)

Which is the most preventive measure against tail damage in finisher pigs: tail docking, straw provision or lowered stocking density?

Animal, 2017
One challenge of intensive pig production is tail damage caused by tail biting, and farmers often decrease the prevalence of tail damage through tail docking.
M. Larsen, H. Andersen, L. Pedersen
semanticscholar   +1 more source

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

Advanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy, Dhyanesh Baskaran, Gaurav Sharma, Wei Hong, Dhanush Gandavadi, Abhichart Krissanaprasit, Joonsu Han, Yusheng Liu, Zack Zimmers, Tshepo Mafokwane, Ichrak Hayah, Neha Chauhan, Mengxi Zheng, Sherwood Yao, Keith Fraser, John S. Decker, Xiaohe Jin, Hua Wang, Adam D. Friedman, Xing Wang   +19 more
wiley   +1 more source

The effect of docking length on the risk of tail biting, tail-directed behaviour, aggression and activity level of growing pigs kept under commercial conditions.

Animal, 2018
Tail biting in domestic pigs relates to a range of risk factors, primarily in the pigs' environment. Preventive tail docking is widely used, and various experimental approaches suggest that docking reduces the risk of tail biting.
K. Thodberg, Mette S. Herskin, Troels S. Jensen, Karin Hjelholt Jensen   +3 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Phytochemical Screening and Antidiabetic Activity of Aqueous Extract of Evolvulus Alsinoides Leaves: An In Vitro and In Silico Study

Journal of Pharmacy and Bioallied Sciences
BackgroundNowadays, diabetes mellitus has become common worldwide due to changes in lifestyle, sedentary life, alterations in food habits, and other genetic and environmental factors. It is necessary to create awareness about the growing pandemic.
Mukundh S Tarun, Veeraraghavan Vishnu Priya, Ponnusamy Bhuvaneswari   +2 more
doaj   +1 more source

Holon: a cybernetic interface for bio-semiotics [PDF]

arXiv
This paper presents an interactive artwork, "Holon", a collection of 130 autonomous, cybernetic organisms that listen and make sound in collaboration with the natural environment. The work was developed for installation on water at a heritage-listed dock in Melbourne, Australia.
arxiv  

The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]

, 2011
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman, Chaim Gilon, Galila Agam, Itshak Levi, Joseph Fanous, Miriam Eisenstein, Orna Almog, Yael Askira, Yftah Talgan   +8 more
core   +1 more source

Urine‐Stable Aptamer‐Conjugated Gold Nanorods for the Early Detection of High‐Grade Bladder Cancer Residual Disease

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni, Silvia Tortorella, Alessandra Caliendo, Irene Locatelli, Alessia Di Coste, Erica Locatelli, Filippo Capancioni, Emanuela Bua, Simona Camorani, Andrea Salonia, Francesco Montorsi, Jithin Jose, Marco Moschini, Laura Cerchia, Mauro Comes Franchini, Massimo Alfano   +15 more
wiley   +1 more source

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil, Tatiana Munteanu, Gaël Brasseur, Carolina Ferreira, Sofia Santos Costa, Isabel Couto, Mohd Athar, Elisa Asunis, Attilio Vittorio Vargiu, Miguel Viveiros, Carole DiGiorgio, Frédéric Brunel, Jean‐Manuel Raimundo, Michel Camplo, Olivier Siri, Jean‐Michel Bolla   +15 more
wiley   +1 more source

GNNAS-Dock: Budget Aware Algorithm Selection with Graph Neural Networks for Molecular Docking [PDF]

arXiv
Molecular docking is a major element in drug discovery and design. It enables the prediction of ligand-protein interactions by simulating the binding of small molecules to proteins. Despite the availability of numerous docking algorithms, there is no single algorithm consistently outperforms the others across a diverse set of docking scenarios.
arxiv