Results 211 to 220 of about 84,234 (259)

Antioxidant and Antidiabetic Activity of the Bulb Extract of <i>Crinum amoenum</i> Roxb. ex Ker Gawl: An Integrated In Vitro, In Vivo and In Silico Approach. [PDF]

Antioxidants (Basel)
Jha PK, Khan K, Abbas A, Weiskirchen R, Kumar Kohar B, Bhattarai N, Yadav RK, Sapkota B, Malik A, Panta S, Pandey B.   +10 more
europepmc   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Antiviral Activity of the Polyene Macrolide Roseofungin Against Influenza a Virus: In Vitro, In Ovo, and Preliminary In Vivo Evaluation. [PDF]

Viruses
Bogoyavlenskiy A, Berezin V, Alexyuk P, Alexyuk M, Zaitseva I, Mukhametkaliyev A, Moldakhanov Y, Anarkulova E, Kerimov T, Dushenkov V.   +9 more
europepmc   +1 more source

Network pharmacology, molecular docking, molecular dynamics and animal experimental validation to investigate the mechanism of hydrocortisone in treating sepsis-induced acute lung injury

Scientific Reports
Shangping Fang, Kecheng Zhai, Xiaoyu Tang, Wanning Li, Huan Li, Cuifeng Zhang, Xianwen Hu, Yongquan Chen   +7 more
openaire   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Comparative Evaluation of White Quinoa and Tri-Color Quinoa on Indomethacin-Induced Gastrointestinal Damage. [PDF]

Food Sci Nutr
Alqahtani NS, Hassan HM, Mohamed HM, Gazaly FM, Sadeek RA.   +4 more
europepmc   +1 more source

Food-Derived Multi-Target Antihypertensive Peptides: Sources, Mechanisms and AI-Driven Strategies. [PDF]

Foods
Zhang M, Liu H, Wang Y, Yu G, Liu M, Lu Z, Mao F, Wu Z, Pan D, Tu M.   +9 more
europepmc   +1 more source

Potential Host-Directed Mechanisms of <i>Houttuynia cordata</i> in <i>Bovine Mycoplasma bovis</i> Pneumonia: A Network Pharmacology and Molecular Docking Study. [PDF]

Vet Sci
Zhao M, Li T, Du L, Deng Q, Mao J, Jia Z, Zhang Y.   +6 more
europepmc   +1 more source

Integration of network pharmacology, molecular docking, and molecular dynamics simulation to elucidate the mechanism of Psychotria rubra in depression treatment. [PDF]

Saudi Pharm J
Yin L, Lu C, Ye J, Zhang Y, Mo S, Wang H.   +5 more
europepmc   +1 more source