Results 141 to 150 of about 3,160,114 (308)

Interaction energy and negative CDOCKER energy of compound 12 obtained from molecular docking simulation.

open access: yes, 2014
Interaction energy and negative CDOCKER energy of compound 12 obtained from molecular docking simulation.
Songmi Kim (131671)   +8 more
core   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Design improvement and analysis of quadrilateral mechanism locks for microsatellite docking systems [PDF]

open access: yes
reservedThe rapid growth of the New Space Economy has led to an increased use of mi-crosatellites and nanosatellites, due to their lower costs and faster development.
GHEDIN, MARCO
core  

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim   +12 more
wiley   +1 more source

Influence of Benincasa hispida Peel Extracts on Antioxidant and Anti-Aging Activities, including Molecular Docking Simulation. [PDF]

open access: yesFoods, 2023
Phumat P   +7 more
europepmc   +1 more source

Tether docking of orbiting spacecraft Final report [PDF]

open access: yes, 1971
Computerized simulation of tether docking by orbiting ...
Greeb, F. J.
core  

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

open access: yesAdvanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan   +16 more
wiley   +1 more source

Position-sensing based a new docking system of RPRS

open access: yes, 2004
Docking is an essential function for Reconfigurable Planetary Robot System (RPRS), it supports almost all metamorphic characteristics of the system. This paper presents a space docking method for self-reconfigurable modular robot system.
Zhang LP(张力平)   +5 more
core  

A piloted simulation study to evaluate the docking control of the LM/ATM vehicle. Project Apollo [PDF]

open access: yes, 1967
Piloted simulation of docking with various configurations of jet failures and solar panels extended or ...
Reid, R.
core  

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

open access: yesAdvanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy