Results 211 to 220 of about 126,162 (305)

Enantioselective synthesis, characterization, molecular docking simulation and ADMET profiling of α-alkylated carbonyl compounds as antimicrobial agents. [PDF]

Sci Rep
Noser AA, Ezzat M, Mahmoud SG, Selim AI, Salem MM.   +4 more
europepmc   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

The Antioxidant Mechanism of Peptides Extracted from Tuna Protein Revealed Using a Molecular Docking Simulation. [PDF]

Antioxidants (Basel)
Guo X, Liu J, Wang C, Wen Z, Zheng B.
europepmc   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

Exploring the potential of 2-arylbenzimidazole scaffolds as novel α-amylase inhibitors: QSAR, molecular docking, simulation and pharmacokinetic studies. [PDF]

In Silico Pharmacol
Aminu KS, Uzairu A, Chandra A, Singh N, Abechi SE, Shallangwa GA, Umar AB.   +6 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Versatile properties of Opuntia ficus-indica (L.) Mill. flowers: In vitro exploration of antioxidant, antimicrobial, and anticancer activities, network pharmacology analysis, and In-silico molecular docking simulation. [PDF]

PLoS One
Mwaheb MA, Reda NM, El-Wetidy MS, Sheded AH, Al-Otibi F, Al-Hamoud GA, Said MA, Aidy EA.   +7 more
europepmc   +1 more source

An accessible microfluidic perfusion platform for time‐restricted control of zebrafish embryonic patterning

Developmental Dynamics, EarlyView.
Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley   +1 more source

From Ship to Shore: A Review of Vessel‐To‐Grid Bidirectional Charging for Sustainable Maritime Transport

EcoEnergy, EarlyView.
As maritime transport electrifies, bidirectional charging (V2G) offers a dual‐purpose solution for energy resilience and economic viability. This work identifies key technological advancements and lifecycle challenges utilizing practical case studies to demonstrate how V2G systems can drive decarbonization and grid stability in the marine sector ...
Jonathan Bloor, Tamer Kamel, Sarah Fear, Lee J. Durndell   +3 more
wiley   +1 more source

Dual‐Functional Sulfonated Nanocellulose for Proton Exchange Membranes With High Proton Conductivity at Low Humidity

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A scalable dual‐functional strategy yields simultaneously sulfonated and nanosized cellulose for proton exchange membranes with continuous hydrogen‐bond networks. These sustainable membranes exhibit low‐humidity proton conductivity twofold higher than Nafion 212, providing a robust solution for next‐generation fuel cells.
Nan Li, Sufeng Zhang, Yali Liu, Jinrui Li, Ning Wei, Chaoyang Li, Tanyanyu Wang   +6 more
wiley   +1 more source