Results 101 to 110 of about 256,731 (319)

Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation [PDF]

, 2014
Cholinesterase inhibitors (ChE-Is) are the standard for the therapy of AD associated disorders and are the only class of approved drugs by the Food and Drug Administration (FDA).
Kuldeep Uchadia, Uchadia, Kuldeep, Chandrabhan Seniya, Ghulam Jilani Khan, Seniya, Chandrabhan, Khan, Ghulam Jilani   +5 more
core   +1 more source

TRAF2 Docking with Related Proteins in Silico Studies

Folia Biologica, 2012
Using the protein-protein docking program, this study investigates the relationship between TRAF2 and its related proteins and the diversity within the 3D structures of TRAF2s. TRAF2 exists in monomer, trimer, and hexamer forms and it can combine with a number of proteins.
F, Zeng, Q, Wu, E, Guo, H, Guo, H, Wang, J, Shan, R, Wei   +6 more
openaire   +2 more sources

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

A longitudinal study of the effects of providing straw at different stages of life on tail-biting and other behaviour in commercially housed pigs [PDF]

, 2011
Tail-biting (TB) is a welfare concern. Recent studies indicate that early provision of straw may help prevent TB, however, many of these studies were carried out on small groups of pigs and may have limited applicability to commercial farms.
Mendl, M. (Michael), Poppy Statham, Statham, Poppy, Green, LE, Mendl, Michael, Green, Laura E., Laura Green, Statham, P, Mendl, M, Green, Laura; id_orcid, Michael Mendl   +10 more
core   +1 more source

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

Advanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo, Linqing Tian, Qiaoyun Wang, Evelyn Szabo, Rebecca Y. Lai, Fariba Dehghani, Martina H. Stenzel   +6 more
wiley   +1 more source

Design improvement and analysis of quadrilateral mechanism locks for microsatellite docking systems [PDF]

reservedThe rapid growth of the New Space Economy has led to an increased use of mi-crosatellites and nanosatellites, due to their lower costs and faster development.
GHEDIN, MARCO
core  

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Molecular docking study of ferulic acid

, 2023
The main purpose of this study is the molecular docking of Ferulic acid with various enzymes such as 2PRG, 6COX, 1HD2, 2HCK, 2IOK, 2Y6W, 2YXJ, 4IEH, 5FDO, 3MWD, 3QNT. A molecular docking study was carried out by AutoDock 4.
Balaji, P., Saravanan, D., Padmavathy, J., Pillai, K.K., Deivam, S.   +4 more
core   +1 more source

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

Advanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

Freight distribution systems with cross-docking: a multidisciplinary analysis [PDF]

Freight transport constitutes one of the main activities that influences economy and society, as it assures a vital link between suppliers and customers and it represents a major source of employment.
Jesus Gonzalez-Feliu
core