Results 91 to 100 of about 1,096,581 (266)

Empathy: Vital in patient care but are we looking at it close enough?

Amrita Journal of Medicine
Empathy is imperative in patient care. Besides enhancing patients’ satisfaction, comfort, and trust, which may facilitate better diagnosis, shared decision-making, and therapy adherence, empathetic doctors experience less burnout, greater job ...
Gokul Gopi, Manish Taywade
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Doctors′ experience and response to unexpected patient death in a Nigerian Teaching Hospital

Journal of Clinical Sciences, 2013
Background and Objective: Negative outcomes in patient care such as death can be an unpleasant experience not only for the affected relatives but also for the members of health care team involved in caring for the patients.
Y O Oshodi, O Kanu, J O Olatosi, A R Erinfolami, O A Lawal, A T Olagunju   +5 more
doaj  

Exploring patient perspectives on Iran’s Electronic Prescription System: a Qualitative Inquiry

Frontiers in Medicine
BackgroundElectronic prescriptions represent a fundamental shift in service delivery, healthcare management, and associated costs, offering numerous advantages. However, akin to other electronic systems, they also present challenges.
Sajed Arabian, Sajed Arabian, Somayyeh Zakerabasali, Mohammad Javad Raee   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Pelayanan Kesehatan bagi Lansia di Desa Bantulan Sleman melalui Kolaborasi Dokter Umum dan Dokter Spesialis

Jurnal Nuansa Akademik
Bantulan Village, located in Godean District, Sleman Regency, is an area with a relatively high elderly population. However, most of the elderly in this area have not received comprehensive health services, especially from specialist doctors capable of ...
Arie Nugroho, Taufik Nur Yahya, Ahmad Mufattan, Viviane Annisa   +3 more
doaj   +1 more source

Doctor Watson Architects: Bots, Collection

, 2018
There is a long tradition in the history of architecture of hybridising sculpture and building, we are currently investigating the possibilities of expanding the same line of enquiry into the realm of artificial intelligence and robotics. We are not only
Watson, V.A.
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source