Results 41 to 50 of about 1,751,019 (301)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cognitive Competence and Curriculum Development in Nurse Anesthesia Education: A Pilot Study

Advances in Medical Education and Practice, 2023
Barry Swerdlow,1 Lisa Osborne-Smith,1,2 Douglas Arditti,1,2 Lisa J Hatfield3 1Nurse Anesthesia Program, Oregon Health & Science University, Portland, OR, USA; 2Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University ...
Swerdlow B, Osborne-Smith L, Arditti D, Hatfield LJ   +3 more
doaj  

ヒト胃癌細胞に対するMDM2阻害剤nutlin-3の抗腫瘍効果に関する研究 [PDF]

, 2011
筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences2010【要旨】Joint authors: Kenji Yamato ... et al.Offprint. Originally published in: Cancer science, v. 102, no. 3, pp.
88949, 遠藤, 慎治
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

University of Applied Sciences Professional Doctorate

, 2021
Hogescholen starten in 2022 met een eigen doctoraatstraject: het Professional Doctorate. Daarmee introduceert het hbo een nieuwe beroepsopleiding waarmee het de grenzen in de beroepspraktijk wil verleggen. Kandidaten worden opgeleid tot hooggekwalificeerde professionals die leren te interveniëren in complexe vraagstukken zoals de energietransitie of de
Andriessen, Daan, van der Zwan, Frank, Vossensteyn, Hans, Paans, Wolter, van Vliet, Harry, van der Giessen, Mariska, Bosma, René, Brezet, Han, Bakker, René, de Bruijn, Elly, van der Velde, Welmoed, van der Sterren, Jos, Stokman, Menno   +12 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Programa de Pós Graduação em Ciências Atmosféricas em Engenharia - 2005 -Teses Defendidas - Doutorado - Instituto de Geociências - UFRJ [PDF]

Anuário do Instituto de Geociências, 2005
213 Anuário do Instituto de Geociências - UFRJ ISSN 0101-9759 Vol. 28-2 / 2005 p. 213-216 Programa de Pós Graduação em Ciências Atmosféricas em Engenharia Teses Defendidas - Doutorado Autora: Célia Maria Paiva Orientadores: Otto Corrêa Rotunno ...
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THE ORIGINS OF MANY DISEASES SHOULD BE SEARCHED IN CHILDHOOD

Мать и дитя в Кузбассе, 2023
Professor of the department, doctor of medical sciences, honored doctor of Russia Yuri Ivanovich Rovda talks about the department of pediatrics and neonatology of the Kemerovo State Medical University, its unique team, scientific directions and his own ...
Юрий Иванович Ровда
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Programa de Pós-Graduação em Geografia - Teses Defendidas 1999 - Doutorado - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]

Anuário do Instituto de Geociências, 1999
131 Anuário do Instituto de Geociências - UFRJ Volume 22 / 1999 Programa de Pós-Graduação em Geografia Teses Defendidas - Doutorado Nome: Carlos Santos Orientador: Lia Osorio Machado Título: A Territorialidade na Colonização em Rondônia Resumo ...
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