Results 51 to 60 of about 273,044 (344)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

A tamper-proof audit and control system for the doctor in the loop

open access: yesBrain Informatics, 2016
The “doctor in the loop” is a new paradigm in information-driven medicine, picturing the doctor as authority inside a loop supplying an expert system with information on actual patients, treatment results, and possible additional (side-)effects ...
Peter Kieseberg   +4 more
semanticscholar   +1 more source

Programa de Pós-Graduação em Geografia - Teses Defendidas 2001- Doutorado - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]

open access: yesAnuário do Instituto de Geociências, 2001
35 Anuário do Instituto de Geociências - UFRJ Volume 24 / 2001 Nome: Cesar Ajara Orientador: Bertha K. Becker Título: Brasil: Espaços incluídos e espaços excluídos na dinâmica da geração de riqueza.
doaj  

Cognitive Competence and Curriculum Development in Nurse Anesthesia Education: A Pilot Study

open access: yesAdvances in Medical Education and Practice, 2023
Barry Swerdlow,1 Lisa Osborne-Smith,1,2 Douglas Arditti,1,2 Lisa J Hatfield3 1Nurse Anesthesia Program, Oregon Health & Science University, Portland, OR, USA; 2Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University ...
Swerdlow B   +3 more
doaj  

Spectrums of investment in Doctor Who fandom

open access: yes, 2006
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Drawing upon a significant weight of empirical data, collected in the field, this thesis proposes a set of four spectrums of investment engaged in by cult ...
Duckworth, Steven J
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Model-driven optimization of multihop wireless networks

open access: yes, 2008
textInterference is fundamental to wireless networks. It is hard to achieve good performance when design routing metrics or algorithms without taking it into account.
Li, Yi, doctor of computer science
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

THE ORIGINS OF MANY DISEASES SHOULD BE SEARCHED IN CHILDHOOD

open access: yesМать и дитя в Кузбассе, 2023
Professor of the department, doctor of medical sciences, honored doctor of Russia Yuri Ivanovich Rovda talks about the department of pediatrics and neonatology of the Kemerovo State Medical University, its unique team, scientific directions and his own ...
Юрий Иванович Ровда
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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