Results 61 to 70 of about 4,453,304 (252)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The problem that there is a contradiction between the article 110 (1) C Undang-Undang Republik Indonesia number 28 year 2009 which is decisive that there is a contribution in the case of reimbursement cost of printing identification cards and article 79A
I Ketut Purna Astha
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Formulating representative features with respect to document genre classification [PDF]
Genre classification (e.g. whether a document is a scientific article or magazine article) is closely bound to the physical and conceptual structure of document as well as the level of depth involved in the text.
Kim, Dr Yunhyong +5 more
core +1 more source
Cum putem citi însemnările neînsemnate [PDF]
There was a custom in the 17th and 18th centuries for the readers of the old books to put down on the pages they were reading some notes about themselves or about the social, political and natural context they were living in.
Cristina Ioana Dima
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Resumo Na continuidade das pesquisas empreendidas com a finalidade de caracterizar a informação na pré-história da Ciência da Informação, vimos buscando marcos documentais e sua traçabilidade, a fim de identificar elementos conceituais inerentes à ...
Icléia Thiesen
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Toward Augmented Document: Expressive Function of Catalog
A library catalog constitutes a communicational tool which allows access to a collection of documents. It contributes to the circulation of knowledge by signaling and locating informational objects.
Caroline Courbieres +2 more
doaj +1 more source

