Results 81 to 90 of about 4,453,304 (252)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Exeter at CLEF 2003: Cross-language spoken document retrieval experiments [PDF]
Cross-Language Spoken Document Retrieval (CLSDR) combines both the complexities of retrieval from collections characterized by speech transcription errors and language translation issues between search requests and documents.
Lam-Adesina, Adenike M. +3 more
core +3 more sources
The objectives of R&D management in NAPS of Ukraine are considered scientific activity as well as connected document types. There is the analysis of requirements for information systems to manage R&D, named “R&D”.
N. Zadorozhna, S. Tukalo, B. Petrushko
doaj
Documents play a central role for many organizational processes. Current conceptualizations of documents predominantly engage with documents in two different ways.
Sebastian Boell, Florian Hoof
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
In response to the concept of an artistic project, technology has a double role: it hides the performer behind the computer and extends the possibilities by representing him/her.
Ana Carvalho
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Laws of External and Internal Design of Business Letter (on the French Materials)
This paper discusses the basic rules of the external and internal design of the business letter. It clarifies that a business letter is a special type of document that has legal effect, so special attention here is given to its design.
Jerome Baghana, Elena Leonidovna Kuksova
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Interlending and document supply
SIGLEAvailable from British Library Document Supply Centre- DSC:4534.4631(3) / BLDSC - British Library Document Supply CentreGBUnited ...
Swires, A.J +1 more
core

