Results 71 to 80 of about 4,453,304 (252)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Preventing document leakage through active document

open access: yes
Electronic documents inside any enterprise environment are assets that add to the enterprise’s capital in intellectual property such as design patents or customer information, securing, these assets is a priority requirement in any security system design.
Crowder, Richard M.   +3 more
core   +1 more source

NILDE: developing a new generation tool for document delivery [PDF]

open access: yes, 2007
This paper presents the most recent progress and implementation of the NILDE (Network Inter-Library Document Exchange) system, which was developed by the National Research Council (CNR) Bologna Research Area Library.
De Matteis, Daniele   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Poéticas del archivo: el “giro documental” en la narrativa rioplatense reciente

open access: yesCuadernos LIRICO, 2019
Río de la Plata’s contemporary literature bears witness to what literary critic Mark Nash refers to as a “documentary turn”. In addition to the incorporation of documentary materials into their texts, the works we designate here as “documentary writings”
Paula Klein
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Examining document model residuals to provide feedback during information retrieval evaluation

open access: yes, 2011
Evaluation of document models for text based Information retrieval is crucial for developing document models that are appropriate for specific domains.
Park, Laurence A. (R15181)
core  

Historia y archivística: memorias del poder

open access: yesCambios y Permanencias, 2012
It seems that Archivistic advances more slowly than history in the process of breaking with its dependence to positivism and functionalism, which tend to bind archives to power and to conceive documents as a source of ...
Ivonne Suárez Pinzón
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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