Results 31 to 40 of about 612,651 (273)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Megaron, 2016 The discussions on ‘authenticity' have always been central in conservation studies. Nowadays, in recent years, the discussions also continued within the debates on the conservation of intangible cultural heritage. This paper brings a new standpoint about
Özlem Karakul
doaj +1 more source
Vanishing viscosity for a $ 2\times 2 $ system modeling congested vehicular traffic
Networks and Heterogeneous Media, 2021 We prove the convergence of the vanishing viscosity approximation for a class of \begin{document}$ 2\times2 $\end{document} systems of conservation laws, which includes a model of traffic flow in congested regimes.
Giuseppe Maria Coclite +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A document management system for the conservation of cultural heritage buildings [PDF]
, 2011 A document management system (DcMS) for the efficient organization and visualization of the data related to conservation projects in cultural heritage buildings applied to a case study is presented.
Amado M. +9 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Road Goes Ever On and On: A Path Through the Wilderness on R.S. 2477 Litigation in Alaska [PDF]
, 2015 Seeking to encourage people to settle the public domain, the federal government established the R.S. 2477 right of way, a grant to construct highways over land in the public domain.
Jackson, Michelle
core +1 more source
Basel III and Responding to the Recent Financial Crisis: Progress made by the Basel Committee in relation to the Need for Increased Bank Capital and Increased Quality of Loss Absorbing Capital [PDF]
, 2010 Developments since the introduction of the 1988 Basel Capital Accord have resulted in growing realisation that new forms of risks have emerged and that previously existing and managed forms require further redress. The revised Capital Accord, Basel II,
Ojo, Mariane.B.
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source