Results 41 to 50 of about 613,640 (292)

Conserving and Documenting Modernism

open access: yesDocomomo Journal, 2022
The Asia Pacific region encompasses more than a quarter of the globe - from pole to pole, from the Middle East to the Pacific. The diversity of climate, geography, culture, history and the sheer scale of the Asia Pacific region make impossible generalizations on the effect and role of "modernism" on architectural thought and practice.
openaire   +2 more sources

Trends in High Nature Value farmland studies: A systematic review [PDF]

open access: yes, 2017
Background. Since the High Nature Value (HNV) concept was defined in the early 1990s, several studies on HNV farmland has been increasing over the past 30 years in Europe, highlighting the interest by scientific community of HNV farming systems
Benedetti, Yanina
core   +3 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Economic benefits of utilizing small sized reservoirs for capture fisheries: the Alau Lake experience [PDF]

open access: yes, 2004
The paper discusses possible approaches to emply in harnessing fish resources in a small sized reservoir. It reveals how capture, extensive and integrated culture fisheries could be beneficially employed to derive maximum gains from the reservoir ...
Abiodun, J.A.   +4 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

The Energy Costs of Historic Preservation [PDF]

open access: yes, 2017
We explore the impact of historical preservation policies on domestic energy consumption. Using panel data for England from 2006 to 2013 and employing a fixed effects strategy, we document that (i) rising national energy prices induce an increase in home
Hilber, C., Palmer, C., Pinchbeck, E.
core  

Distribution, Habitat, and Life History Aspects of the Dwarf Crayfishes of the Genus Cambarellus (Decapoda: Cambaridae) in Arkansas [PDF]

open access: yes, 2019
The dwarf crayfishes of the genus Cambarellus are represented in Arkansas by only 2 species: Cambarellus (Pandicambarus) puer (Hobbs) and C. (P.) shufeldtii (Faxon). Both species are quite small and uncommonly encountered in the state.
McAllister, Chris T., Robison, Henry W
core   +3 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Management of Phytophthora cinnamomi for biodiversity conservation in Australia: Part 2. National best practice guidelines [PDF]

open access: yes, 2005
Disease in natural ecosystems of Australia, caused by the introduced plant pathogen Phytophthora cinnamomi, is listed as a key threatening process under the Environment Protection and Biodiversity Conservation Act 1999 (EPBC Act).
Hardy, G.E.St.J.   +3 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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