Results 41 to 50 of about 4,367,374 (298)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Digital agriculture informational resources in local and international databases

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2021
The article reviews informational resources on precision and digital agriculture in international cross-disciplinal and sectoral international and local databases.
M. S. Bunin   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Re-engineering relational databases [PDF]

open access: yes, 2011
This paper surveys the recent literature about various research trends relevant to Relational DataBase (RDB) reengineering. The paper presents an analysis of approaches and techniques used in this context, including construction of object views on top of
Ali, Akhtar   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

An Arabic intelligent interface for accessing NoSQL document-oriented databases

open access: yesSystems and Soft Computing
NoSQL document-oriented databases are widely used to manage large volumes of unstructured and semi-structured data, especially in web applications and Big Data environments.
Hanane Bais, Mustapha Machkour
doaj   +1 more source

Reshaping Smart Businesses with Cloud Database Solutions [PDF]

open access: yesDatabase Systems Journal, 2015
The aim of this article is to show the importance of Big Data and its growing influence on companies. We can also see how much are the companies willing to invest in big data and how much are they currently gaining from their big data.
Bogdan NEDELCU   +3 more
doaj  

Slant Removal Technique for Historical Document Images

open access: yesJournal of Imaging, 2018
Slanted text has been demonstrated to be a salient feature of handwriting. Its estimation is a necessary preprocessing task in many document image processing systems in order to improve the required training.
Ergina Kavallieratou   +2 more
doaj   +1 more source

Experimental Evaluation of Graph Databases: JanusGraph, Nebula Graph, Neo4j, and TigerGraph

open access: yesApplied Sciences, 2023
NoSQL databases were created with the primary goal of addressing the shortcomings in the efficiency of relational databases, and can be of four types: document, column, key-value, and graph databases.
Jéssica Monteiro   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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