Results 61 to 70 of about 122,251 (308)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

ASP en bibliotecas y centros de documentación : publicación de una base de datos Microsoft Access en el web

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2000
Es descriuen els passos necessaris per publicar a Internet una base de dades creada amb Microsoft Access utilitzant la tecnologia ASP. Es parteix d'un exemple de base de dades creada per a controlar el procés d'adquisicions i es van resseguint, en forma ...
Rodríguez-Gairín, Josep-Manuel
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Analysis and comparison of document databases

open access: yes, 2022
Glavni cilj diplomskega dela, je bilo raziskati ter medsebojno analizirati dokumentne podatkovne baze. V teoretičnem delu smo te predstavili, ter podrobneje analizirali štiri izmed njih.
Turk, Jure
core  

Revistes font en el SCI-E

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2003
L’objectiu del text és determinar si les revistes incloses a la base de dades Science citation index.Expanded (SCI-E) són revistes font com ho són les que s’inclouen al Science citation index (SCI) per a la posterior publicació dels indicadors ...
Badia Segura, Maria   +2 more
doaj  

Design and implementation of a document database extension [PDF]

open access: yes, 2006
Integration of text and documents into database management systems has been the subject of much research. However, most of the approaches are limited to data retrieval. Collaborative text editing, i.e. the ability for multiple users to work on a document instance simultaneously, is rarely supported.
Leone, Stefania   +4 more
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A Model-Driven Approach to Generate Schemas for Object-Document Mappers

open access: yesIEEE Access, 2019
Many actual NoSQL systems are schemaless, that is, the structure of the data is not defined beforehand in any schema, but it is implicit in the data itself. This characteristic is very convenient when the data structure suffers frequent changes. However,
Alberto Hernandez Chillon   +3 more
doaj   +1 more source

The Replication Database: Documenting the Replicability of Psychological Science [PDF]

open access: yesJournal of Open Psychology Data
In psychological science, replicability—repeating a study with a new sampleachieving consistent results (Parsons et al., 2022)—is critical for affirming the validity of scientific findings. Despite its importance, replication efforts are few and far between in psychological science with many attempts failing to corroborate past findings. This scarcity,
Lukas Röseler   +96 more
openaire   +12 more sources

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