Results 71 to 80 of about 601,118 (275)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

GenAI-Assisted Database Deployment for Heterogeneous Indigenous–Native Ethnographic Research Data

open access: yesApplied Sciences
In ethnographic research, data collected through surveys, interviews, or questionnaires in the fields of sociology and anthropology often appear in diverse forms and languages.
Reen-Cheng Wang   +4 more
doaj   +1 more source

Databases and Documenting Data

open access: yesSignificance, 2007
Abstract Codebooks are usually associated with spies and concealed information. Allan Reese proposes statisticians should adopt codebooks but for the opposite purpose, making data more understandable. Without a codebook, you are working in the dark.
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

GenIsisWeb : la herramienta para publicar en Internet las bases de datos CDS/ISIS

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2003
El objetivo de la reseña es presentar GenIsisWeb, un programa que asiste en la publicación de bases de datos en Internet. Tras una breve descripción técnica y partiendo de una base de datos previamente creada con CDS/ISIS, se muestra el proceso completo ...
Alcàzar, Noemi, Chávez, Sergi
doaj  

A Model-Driven Approach to Generate Schemas for Object-Document Mappers

open access: yesIEEE Access, 2019
Many actual NoSQL systems are schemaless, that is, the structure of the data is not defined beforehand in any schema, but it is implicit in the data itself. This characteristic is very convenient when the data structure suffers frequent changes. However,
Alberto Hernandez Chillon   +3 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Multilingual Access to Document Databases

open access: yesProceedings of the Annual Conference of CAIS / Actes du congrès annuel de l'ACSI, 2013
This paper examines the reasons why approaches to facilitate document retrieval which apply AI (Artificial Intelligence) or Expert Systems techniques, relying on so-called "natural language" query statements from the end-user will result in sub-optimal solutions.
Steven A. Pollitt, Geoff Ellis
openaire   +1 more source

Index to Library Trends Volume 38 [PDF]

open access: yes, 1990
published or submitted for ...
Pandit, Idrisa
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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