Results 101 to 110 of about 7,850,357 (294)
Development and deployment of document management technology into Rover : executive summary [PDF]
Document Management is a technology that allows the input, storage, management and control of an image under the supervision of a computer based system.
Smith, C. L. R.
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The diagnosis and treatment of peripheral lymphedema: 2016 Consensus Document of the International Society of Lymphology [PDF]
, 2017 This International Society of Lymphology (ISL) Consensus Document is the latest revision of the 1995 Document for the evaluation and management of peripheral lymphedema [1].
Document, Consensus
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Recent Developments in Remote Document Supply in the UK [PDF]
, 2004 Recent trends and developments in remote document supply in the UK are examined, including a suggestion of what to call the activity itself. The impact of recent legislation covering copyright, legal deposit and electronic signatures on RDS is discussed ...
Prowse, Stephen
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Pretraživanje multimedijalnih informacija u sistemu digitalnih biblioteka magistarskih i doktorskih radova = Multimedia document retrieval in the networked digital library of theses and dissertations [PDF]
, 2004 There is a number of systems providing retrieval of multimedia documents. These systems have certain shortcomings, such as fixed document structure and a limited number of supported media types.
Milosavljević, Branko, Konjović, Zora
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Study on the characteristics and mechanism of antibiotic pollution in different aquifers
Shuiwen dizhi gongcheng dizhiThe risk posed by antibiotics in various aquifers has attracted wide attention. This study investigated the pollution characteristics and controlling factors of antibiotics in different types of aquifers, and identified the indicator factors of ...
Jialin WANG, Jinwei PAN, Fei LIU
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source