Results 101 to 110 of about 599,620 (310)

Película la muerte de Jaime Roldós: ¿documental o reportaje?

open access: yes, 2019
La siguiente disertación tiene como objetivo principal comparar las diferencias entre reportaje periodístico y cine documental a través de la película ecuatoriana “La muerte de Jaime Roldós” de los autores Manolo Sarmiento y Lisandra Rivera.
Valencia Salcedo, Daniel Bolívar
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Análisis de las ventajas y desventajas del sistema de gestión documental QUIPUX para la PUCESE

open access: yes, 2017
Tesis previa obtención del título de Magister en Administración de Empresas Mención PlaneaciónEl presente trabajo de investigación tiene como objetivo analizar las ventajas y desventajas del sistema de gestión documental Quipux en la Pontificia ...
Bateoja Arroyo, Holga
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Presencia de las bases de datos del CSIC en las bibliotecas universitarias y científicas españolas: descripciones y materiales didácticos para la formación de usuarios

open access: yesRevista Española de Documentación Científica, 2009
Luis Rodríguez-Yunta   +2 more
doaj   +1 more source

Cuadro de Clasificación Documental

open access: yes, 2018
Cuadro de Clasificación Documental - Universidad Militar Nueva ...
Universidad Militar Nueva Granada
core  

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