Results 51 to 60 of about 1,009,209 (280)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Periferias genéricas: la crónica y el documental frente a las urbanizaciones privadas
Kamchatka: Revista de Análisis Cultural, 2015 Resumen: En la Argentina de la primera década del siglo XXI, las urbanizaciones cerradas fueron escenario de diversas obras de ficción literaria y fílmica que parecían hacer eco a la atención mediática que reclamaban tanto la consolidación del fenómeno ...
Mercedes Alonso
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Kamchatka: Revista de Análisis Cultural, 2017 Resumen: El presente artículo aborda el cine moderno latinoamericano a partir de la articulación del cortometraje y el documental en tanto agentes fundamentales en el asentamiento de este fenómeno en la región.
Javier Cossalter
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Designing the venue logistics management operations for a World Exposition [PDF]
, 2014 World Expositions, due to their size and peculiar features, pose a number of logistics challenges. This paper aims at developing a design framework for the venue logistics management (VLM) operations to replenish food products to the event site, through ...
Colicchia, Claudia +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
La norma ISO 15489:2001 y su evolución hacia un cambio de estrategia en las organizaciones
Acervo, 2015 Analisa a norma ISO 15489, suas características e perspectivas, bem como o modelo que propõe a implantação de um sistema de gestão de documentos nas organizações, sua relação com os sistemas de qualidade e a mudança de estratégia acarretada pelo ...
Joaquim Llansó Sanjuan
doaj
Intranet de gestión documental [PDF]
, 2013 Aquest projecte es basa en la creació d'una intranet de gestió documental personalitzada i adequada a les necessitats de l'empresa. És una eina basada en la comunicació de l'empresa amb els treballadors des de qualsevol part del mon y per sobre de tot ...
Costela Travé, Abel +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source