Results 61 to 70 of about 371,509 (298)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Palliative care: A proposal for undergraduate education in Medicine
Objective: to propose essential competencies for the teaching of palliative care on undergraduate Medicine courses. Method: a documentary analysis of the literature on general competencies in palliative care was initially carried out, to construct a ...
Gustavo Henrique de Oliveira Caldas +2 more
doaj +2 more sources
Cinema of poverty: Independence and simplicity in an age of abundance and complexity [PDF]
Over the past 25 years of writing, producing and directing, my aspirations as a creative artist in film have shifted from a paradigm in which the scale and scope of financial and human resources shaped not only the creative intentions of a project, but ...
Knudsen, E
core
The Convergence Review and the future of Australian content regulation [PDF]
This article examines the place of Australian and local content regulation in the new media policy framework proposed by the Convergence Review. It outlines the history of Australian content regulation and the existing policy framework, before going on ...
Goldsmith, Ben, Thomas, Julian
core +4 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Documentary Filmmakers' Statement of Best Practices in Fair Use [PDF]
Clarifies common misunderstandings about fair use doctrine and presents a formal guideline, organized around four classes of copyright situations that documentary filmmakers and artists confront regularly in practice, for determining fair ...
core
Broadcasting graphic war violence: the moral face of Channel 4 [PDF]
Drawing on empirical data from Channel 4 (C4) regarding the broadcasting of violent war imagery, and positioned within Goffman’s notion of the interaction ritual (1959, 1967), this article investigates how C4 negotiate potentially competing commercial ...
BBC2 +24 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The purpose of this paper is to present the activity of foreigners in the port city of Galatz, during the first half of the 19th century. Consulted material included documentary sources, monographs, and historical synthesis.
CHEŞCU Ana-Maria
doaj

