Results 91 to 100 of about 13,578,871 (275)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Discourse Analysis of the Documentary Method as "Key" to Self-Referential Communication Systems? Theoretic-Methodological Basics and Empirical Vignettes

open access: yesForum: Qualitative Social Research, 2010
Niklas LUHMANN is well known for his deliberate departure from the classical focus on studying individual actions and directing attention on the actors' relatedness through so called (autopoietic) communication systems.
Gian-Claudio Gentile
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

How to Analyse Interviews: A Documentary Method of Interpretation

open access: yesCoRR
Interviews are commonplace in HCI. This paper presents a documentary method of interpretation (DMI) for the analysis of the topical organisation of talk within a corpus of transcripts, topics that are endogenous to it and elaborate patterns of social reasoning about issues of relevance to research. The DMI reflexively enables endogenous topic analysis (
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Braided Channels: A Genealogy of the Voice of Documentary

open access: yes, 2009
Voice is a concept that is a metaphoric proxy for authorship in a wide range of areas of human creativity. In the area of documentary filmmaking, Bill Nichols' conception of voice has been pre-eminent, dating from a 1983 essay 'The Voice of Documentary ...
Fitzsimons, T, Trish FitzSimons
core   +1 more source

Steering Committee Members in School Networks: Distinctions in Admission Processes

open access: yesForum: Qualitative Social Research, 2010
School networks—defined as people cooperating in order to initiate and emphasize school and professional development—have been established in German speaking areas since the beginning of the 1990s.
Tanja Sturm
doaj  

Science Education and Documentary Method:Applications and Refinements of the Documentary Method for Science Education Research

open access: yes, 2023
In this article, a theoretical and methodological framing of the Documentary Method in the context of science education is presented. After a short overview of research contributions in science education that are based on the Documentary Method, its theoretical foundations, central terminology and methodical procedures are presented and examples are ...
Rabe, Thorid   +2 more
openaire   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Politikum a privatum. O podobách ruskej dokumentárnej drámy // Politicum and privatum: Different representations of the Russina documentary drama [PDF]

open access: yesSvět Literatury, 2016
In 2002, the theatre Teatr.doc was established in the Moscow by the group of Russian playwrights led by Yelena Gremina and Mikhail Ugarov. The verbatim method and documentary drama became a new trend of their performing arts creation.
Romana Štorková Maliti
doaj  

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